Nutraceuticals in the management of diabetes mellitus

Nimesh, Saurabh; Ashwlayan, Vrish Dhwaj

doi:10.15406/ppij.2018.06.00166

Cited by 13 publications

(9 citation statements)

References 52 publications

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“…Phytochemicals (flavanols, phenolics), which have antioxidants, anti-diabetic and anti-inflammatory effects, and dietary fiber (soluble and insoluble fibers), delay carbohydrate digestion and absorption as a means of controlling glycemic levels [53]. L-carnitine is derived through dietary sources (such as meat and dairy products) as well as biosynthesis from lysine and methionine [80]. L-carnitine improves insulin sensitivity, decreases insulin resistance, and has lipid-lowering characteristics [54].…”

Section: (A) Functional Foodsmentioning

confidence: 99%

Impact of Nutraceuticals on Type 1 and Type 2 Diabetes Mellitus-Induced Micro- and Macrovasculopathies

Mabena,

Fasemore,

Nkomozepi

2023

Applied Sciences

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Diabetes mellitus (DM), one of the most serious non-communicable diseases, has long-term negative effects on the healthcare system due to its microvascular and macrovascular manifestations, which can be fatal if left untreated. Nutraceuticals, on the other hand, are alternative therapy choices of orally consumed natural food ingredients applicable in the management of several diseases, including diabetes mellitus. Through their antioxidant capabilities and bioactive components, nutraceuticals have been clinically demonstrated to be effective in preventing a number of ailments, including cancer, diabetes, heart disease, and kidney problems. Flavonoids, which are categorized as phytochemicals, are present in several of these nutraceuticals. Cocoa, one of the flavanols engaged in the treatment of diabetes mellitus, provides an additional non-pharmaceutical intervention in the management of diabetes mellitus, which, in part, is because of its high antioxidant capacity. Additionally, flavonoids improve insulin resistance and sensitivity, dyslipidemia, endothelial function, and blood pressure, as well as lower oxidative stress and inflammatory processes. As a result, they may be able to stop the progression of long-term vascular consequences of diabetes, such as cardiovascular disease, neuropathy, nephropathy, and retinopathy. Therefore, the effects of nutraceuticals (as an alternative treatment) on diabetic-related micro- and macrovascular problems are the main focus of this review.

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Section: (A) Functional Foodsmentioning

confidence: 99%

Impact of Nutraceuticals on Type 1 and Type 2 Diabetes Mellitus-Induced Micro- and Macrovasculopathies

Mabena,

Fasemore,

Nkomozepi

2023

Applied Sciences

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“…The food that contains high fibber includes fruits, vegetables, nuts, and wheat. The beverages with high sugar ingredient should also be avoided [1].…”

Section: Healthy Dietmentioning

confidence: 99%

“…In the recent years, the number of people living with diabetes is considerably high. In the global level, this number has quadrupled in the past three decades [1]. About 1 from 11 adults currently suffer from this disease worldwide, and 90% of them are with type 2 Diabetes Mellitus (T2DM).…”

Section: Introductionmentioning

confidence: 99%

Analysis of Diabetes Mellitus Prevalence Number of the People of Horai–Quic, Maubesi, Ainaro, Timor Leste and its correlation with Their Lifestyle

Rejeki¹,

Pratiwi²,

Owa³

2021

Proceedings of the 2nd Borobudur International Symposium on Humanities and Social Sciences, BIS-HSS 2020, 18 November 2020, Mag

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Diabetes Mellitus is metabolic disorder disease where body prevents to convert carbohydrate into energy. This disease is mainly indicated by excessive glucose level in blood causing medical complications that may lead to deadly effect. The prevalence number of this disease increases persistently and more than 45% of the cases are undiagnosed. People of Timor Leste have lifestyle that strongly leads to the risk of suffering from Diabetes Mellitus. Some people do not receive proper formal education, some of them are jobless and their lifestyle is not quite healthy. In term of medical literacy, people of Timor Leste do not have sufficient knowledge on this subject. Since Diabetes Mellitus may not indicate significant physical problem, people who starts having this disease may not feel any serious problem. On the other hand, the facility of medical service is not really sufficient to provide initial diagnose for Diabetes Mellitus and, as a result, some people are not aware that they are suffering from the disease. A test was carried for the people of Horai-Quic, Maubesi, Ainaro, Timor Leste, aged 25 -50 year. From the 47 people participating the test, it was identified that 40 people (85.11%) tend to suffer from Diabetes Mellitus. Some lifestyles are described and analyzed, and their impact on the possibility of having the disease will be highlighted.

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“…Nutraceuticals are supplements that contain lipids, vitamins, carbohydrates, proteins, minerals, or other essential ingredients. Nutraceuticals have been found to be potential agents in the treatment of a variety of maladies, including cardiovascular disease 2,3 , diabetes 4,5 , atherosclerosis 6,7 , cancer 8,9 and neurological disorders 10,11 .…”

Section: Introductionmentioning

confidence: 99%

A Brief Review on Nutraceuticals and its Application

Jain

Purohit

Nema

et al. 2022

Asian J Dental Health Sci

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Because of their putative safety, nutraceuticals have sparked tremendous interest. Nutraceuticals are nutritional supplements that are used to improve health, postpone aging, prevent disease and support the healthy functioning of the human body. Nutraceuticals are currently gaining popularity due to their nutritional and medicinal properties. They are classified as dietary supplements or herbal bioactive substances based on their source. Herbal nutraceuticals aid in the maintenance of health and the promotion of optimal health, longevity, and quality of life. Nutraceuticals have demonstrated encouraging results in the treatment of a variety of ailments, including cancer, neurological diseases, cardiovascular disease, and others. The current review provides an overview of several bioactive substances that operate as nutraceuticals (carbohydrates, lipids, edible flowers, alkaloids, medicinal plants, etc.) and their involvement in health benefits. Focus on the need for appropriate diets, health issues associated with failure to adhere to known healthy eating models, development of new nutraceuticals/functional foods/food supplements with novel health benefits, elucidation of mechanisms of action of these products, and to define and understand the analytical, formulation, and regulatory aspects of nutraceuticals. The use of nutraceuticals in the prevention of certain diseases has also been addressed. Keywords: Nutraceutical, Dietary supplements, Herbal bioactive compounds, Application

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Nutraceuticals in the management of diabetes mellitus

Cited by 13 publications

References 52 publications

Impact of Nutraceuticals on Type 1 and Type 2 Diabetes Mellitus-Induced Micro- and Macrovasculopathies

Impact of Nutraceuticals on Type 1 and Type 2 Diabetes Mellitus-Induced Micro- and Macrovasculopathies

Analysis of Diabetes Mellitus Prevalence Number of the People of Horai–Quic, Maubesi, Ainaro, Timor Leste and its correlation with Their Lifestyle

A Brief Review on Nutraceuticals and its Application

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