Nutraceuticals as a natural alternative for preventive and proactive health care

Visen, Aastha; Visen, Srishti; Sharma, Asha; Visen, Pradeep Kumar Singh

doi:10.1016/b978-0-12-819815-5.00040-9

Cited by 4 publications

(3 citation statements)

References 64 publications

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“…Natural bioactive substances can both inhibit and prevent all types of cancer. Globally, there is a greater demand for products made from plants for therapeutic and nutraceutical uses as a result of research being conducted to determine which chemical compounds are present in each plant and their various pharmacological activities [19]. The methanolic extract of C. Cartilaginea fruit contains a steroid, carbohydrate, alkaloid, saponins, and flavonoids [9,11]).…”

Section: Phytochemical Screening By Gc-ms Analysismentioning

confidence: 99%

GC-MS analysis of the bioactive phytochemical compounds with anticancer activity in the Capparis cartilaginea fruit extracts

Sonbol¹,

Hosawi²,

Hosawi³

2023

J Adv Pharm Educ Res

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Section: Phytochemical Screening By Gc-ms Analysismentioning

confidence: 99%

GC-MS analysis of the bioactive phytochemical compounds with anticancer activity in the Capparis cartilaginea fruit extracts

Sonbol¹,

Hosawi²,

Hosawi³

2023

J Adv Pharm Educ Res

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“…Even though plant sources are potential antidiabetic drugs, they have not gained sufficient momentum among the scientific community. In recent times, it is understood that a proper nutritional regulation with appropriate herbs in our diet shall help to reduce the incidence of diabetes ( 9 ). S. torvum fruit is also infrequently used by a section of a population as a vegetable.…”

Section: Introductionmentioning

confidence: 99%

Antidiabetic activity of Solanum torvum fruit extract in streptozotocin-induced diabetic rats

Satyanarayana¹,

Chinni

Gobinath

et al. 2022

Front. Nutr.

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BackgroundSolanum torvum Swartz, a medicinal plant belonging to the family Solanaceae, is an important medicinal plant widely distributed throughout the world and used as medicine to treat diabetes, hypertension, tooth decay, and reproductive problems in traditional systems of medicine around the world including Malaysia. The objective of this study was to investigate hypoglycemic, antilipidemic, and hepatoprotective activities, histopathology of the pancreas, and specific glucose regulating gene expression of the ethanolic extract of S. torvum fruit in streptozotocin-induced diabetic Sprague–Dawley rats.Materials and methodsAcute toxicity study was done according to OECD-423 guidelines. Diabetes was induced by intraperitoneal (i.p.) injection of streptozotocin (55 mg/kg) in male Sprague–Dawley rats. Experimental diabetic rats were divided into six different groups; normal, diabetic control, and glibenclamide at 6 mg/kg body weight, and the other three groups of animals were treated with oral administration of ethanolic extract of S. torvum fruit at 120, 160, and 200 mg/kg for 28 days. The effect of ethanolic extract of S. torvum fruit on body weight, blood glucose, lipid profile, liver enzymes, histopathology of pancreas, and gene expression of glucose transporter 2 (slc2a2), and phosphoenolpyruvate carboxykinase (PCK1) was determined by RT-PCR.ResultsAcute toxicity studies showed LD50 of ethanolic extract of S. torvum fruit to be at the dose of 1600 mg/kg body weight. Blood glucose, total cholesterol, triglycerides, low-density lipoproteins, very low-density lipoproteins, serum alanine aminotransferase, and aspartate aminotransferase were significantly reduced, whereas high-density lipoproteins were significantly increased in S. torvum fruit (200 mg/kg)-treated rats. Histopathological study of the pancreas showed an increase in number, size, and regeneration of β-cell of islets of Langerhans. Gene expression studies revealed the lower expression of slc2a2 and PCK1 in treated animals when compared to diabetic control.ConclusionEthanolic extract of S. torvum fruits showed hypoglycemic, hypolipidemic, and hepatoprotective activity in streptozocin-induced diabetic rats. Histopathological studies revealed regeneration of β cells of islets of Langerhans. Gene expression studies indicated lower expression of slc2a2 and PCK1 in treated animals when compared to diabetic control, indicating that the treated animals prefer the gluconeogenesis pathway.

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“…With increased health awareness and dietary trends toward healthier foods, the popularity, production, and marketing of functional food crops such as taro have increased. These types of crops can be used as both functional herbal medicinal and food crops, as well as plant‐based nutritional components for therapeutic, nutraceutical, and pharmaceutical purposes (Visen et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Industrial applications of taro (Colocasia esculenta) as a novel food ingredient: A review

Shah

Saeed

Afzaal

et al. 2022

Food Processing Preservation

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Taro is an annual herbaceous plant grown in tropical and subtropical regions. Its various parts including corms and leaves are rich in vitamins (C, thiamine, and riboflavin), minerals (calcium and phosphorus), starch, and various bioactive compounds. The phytochemicals and pharmacological potential of taro are effective in mitigating various health maladies including neurological disorders, internal hemorrhage, and cancer. Furthermore, taro possessed various functional properties having various commercial aspects. Taro starch has multifarious potential in the food industry. Taro is a novel ingredient being used as an emulsifier, stabilizer, and prebiotic for the development of various products. It is a rich source of mucilage used in the preparation of various products. The results of various studies endorsed that taro has promising prebiotic potential and is linked to the modulation of healthy gut microbiota. The nutritional, therapeutic, biological, pharmacological, and functional properties are in the limelight of the current review. Novelty impact statement Taro and its parts, such as the stem, corm, and leaves, are high in fiber and vital nutrients and offer a wide range of health benefits, including improved blood sugar management, gut health, and cardiovascular health. Taro starch has a wide range of applications in the food industry. It is a unique ingredient that has been used as an emulsifier, stabilizer, and prebiotic in the development of a variety of food products. Various research has found that taro has key bioactive components and can be utilized to develop a variety of functional foods and nutraceuticals.

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Nutraceuticals as a natural alternative for preventive and proactive health care

Cited by 4 publications

References 64 publications

GC-MS analysis of the bioactive phytochemical compounds with anticancer activity in the Capparis cartilaginea fruit extracts

GC-MS analysis of the bioactive phytochemical compounds with anticancer activity in the Capparis cartilaginea fruit extracts

Antidiabetic activity of Solanum torvum fruit extract in streptozotocin-induced diabetic rats

Industrial applications of taro (Colocasia esculenta) as a novel food ingredient: A review

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