Background: Childhood immunization against common childhood diseases is the most powerful public health strategy to keep children healthy. It has been the most cost-effective public health intervention, saving an estimated 2-3 million lives around the world each year. However, because no vaccine is 100% safe and effective, so adverse events post-immunization may occur. These adverse events are any untoward medical occurrences that occur following immunization and do not necessarily have a causal relationship with the use of the vaccine. Moreover, if not rapidly and effectively dealt with it, it can undermine confidence in a vaccine and ultimately have dramatic consequences for immunization coverage and disease incidence.