Nurses’ Attitudes Toward Clinical Research

Browning, Brittan; Page, Karen; Kuhn, Renee; DiLiberto, Mary Ann; Deschenes, Jendar; Taillie, Eileen; Tomanio, Elyse; Holubkov, Richard; Dean, Jonathan; Moler, Frank W.; Meert, Kathleen L.; Pemberton, Victoria L.

doi:10.1097/pcc.0000000000000609

Cited by 7 publications

(4 citation statements)

References 23 publications

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“…[17] Hypothermia occurs when heat loss exceeds metabolic heat production. [18] Although the use of hypothermia in the pediatric population is helpful for treating brain injury and cardiac arrest, [19,20] infants are considered to have a greater risk of developing unplanned hypothermia than adults because of a high body surface area to mass ratio, higher metabolic rate, difference in body size, limited stores of subcutaneous fat, and a less effective regulatory capacity. [5,21–23] Major surgeries can increase the chance of decrease in the infant's CBT.…”

Section: Discussionmentioning

confidence: 99%

Clinical effects of warmed humidified carbon dioxide insufflation in infants undergoing major laparoscopic surgery

Meng-Meng¹,

Xu²,

Xiao-Hong³

2019

Medicine

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Purpose: Some studies have reported that warmed humidified carbon dioxide (CO 2 ) insufflation in adult laparoscopic surgery could reduce pain and improve the core body temperature (CBT). However, similar studies are lacking in infants. Thus, this study aimed to investigate the clinical effects of warmed, humidified CO 2 insufflation in pediatric patients undergoing major laparoscopic surgeries. Methods: From January 2015 to December 2017, infants who underwent major laparoscopic surgeries in Ningbo Women and Children's Hospital were randomized to Group A (standard CO 2 insufflation) or Group B (warmed humidified CO 2 insufflation, 35°C, 95% relative humidity). Change in CBT at the end of surgery was the primary outcome. Secondary outcomes included surgery time, intraoperative blood loss, oxygen saturation (SO 2 ), and Face, Legs, Activity, Cry and Consolability (FLACC) scale. These variables were compared between the 2 groups. Results: Sixty-three infants (38 females, 25 males) were included; 30 patients were in Group A and 33 in Group B. The diseases treated with the laparoscopic approach included congenital megacolon, congenital diaphragmatic hernia, and intestinal malrotation. No deaths were noted. CBT was significantly higher in Group B at the end of surgery ( P = .021). The occurrence of postoperative shivering ( P = .02), hypothermia ( P = .032), bowel movement ( P = .044), and hospital stay ( P = .038) was significantly different between the 2 groups; Group B had less shivering and hypothermia occurrence after surgery. Moreover, Group B demonstrated a more rapid postoperative recovery of bowel movement and shortened hospital stay than Group A. There was no statistical difference in operative time ( P = .162), intraoperative blood loss ( P = .541), SO 2 ( P = .59), and FLACC scale ( P = .65) between the 2 groups. Conclusion: The use of warmed humidified CO 2 insufflation in infants undergoing major laparoscopic surgery was helpful for maintaining normothermia and was associated with several positive postoperative outcomes, including less shivering and hypothermia, faster recovery of bowel movement, and shortened hospital stay.

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Section: Discussionmentioning

confidence: 99%

Clinical effects of warmed humidified carbon dioxide insufflation in infants undergoing major laparoscopic surgery

Meng-Meng¹,

Xu²,

Xiao-Hong³

2019

Medicine

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“…More than half (55%) of children enrolled underwent ECMO after cardiac arrest and before randomization ( 30 ). Recommendations for best practices for informed consent and methods of support during the consent process have been published and should be followed for any future pediatric ECMO studies ( 50 , 51 ).…”

Section: Methodological Challenges In Pediatric Ecmo Researchmentioning

confidence: 99%

Pediatric ECMO Research: The Case for Collaboration

2018

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The use of extracorporeal membrane oxygenation (ECMO) in the pediatric age has increased considerably in the last decade, as has the complexity of cases and the variety of indications outside of the neonatal age. However, no randomized controlled trials have been attempted to date to test ECMO as an intervention in non-neonatal pediatric patients with critical illness. In this review, we provide a brief overview of the history of clinical research in pediatric ECMO and discuss methodological challenges including heterogeneity of ages and diagnoses in the pediatric ECMO population, rapid advances in technology and clinical practice related to ECMO, feasibility of enrolling critically ill children on ECMO in clinical research studies, and variability in ECMO management across institutions and countries. Lastly, we discuss opportunities and existing infrastructure for future multicenter, multi-network research collaborations for pediatric ECMO studies.

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“…Of the survey respondents, 188 self-identified as nurses or nurse practitioners. A predominant number of nurses were from the United States (78%; 10 Browning et al 12 Nurse is viewed as closest ally for infants/families. Nurses' perceptions toward clinical trials may impact the families' decision to participate.…”

Section: Sample Demographicsmentioning

confidence: 99%

Nurses' Knowledge, Communication Needs, and Future Directions in Neonatal Research

Beauman

Eklund²,

Short³

et al. 2023

Advances in Neonatal Care

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Background: Preterm birth is a significant contributor to neonatal morbidity and mortality. Despite legislative efforts to increase pediatric drug development, neonatal clinical trials continue to be infrequent. The International Neonatal Consortium (INC) includes nurses as key stakeholders in their mission to accelerate safe and effective therapies for neonates. Purpose: INC developed a survey for nurses, physicians, and parents to explore communication practices and stakeholders' perceptions and knowledge regarding clinical trials in neonatal intensive care units (NICUs). Methods: A stepwise consensus approach was used to solicit responses to an online survey. The convenience sample was drawn from INC organizations representing the stakeholder groups. Representatives from the National Association of Neonatal Nurses and the Council of International Neonatal Nurses, Inc, participated in all stages of the survey development process, results analysis, and publication of results. Results: Participants included 188 nurses or nurse practitioners, mainly from the United States, Canada, the European Union, and Japan; 68% indicated some level of research involvement. Nurses expressed a lack of effective education to prepare them for participation in research. Results indicated a lack of a central information source for staff and systematic approaches to inform families of studies. The majority of nurses indicated they were not asked to provide input into clinical trials. Nurses were uncertain about research consent and result disclosure processes. Implications for Practice and Research: This study indicates the need to educate nurses in research, improve NICU research communication through standardized, systematic pathways, and leverage nurse involvement to enhance research communication.

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Nurses’ Attitudes Toward Clinical Research

Cited by 7 publications

References 23 publications

Clinical effects of warmed humidified carbon dioxide insufflation in infants undergoing major laparoscopic surgery

Clinical effects of warmed humidified carbon dioxide insufflation in infants undergoing major laparoscopic surgery

Pediatric ECMO Research: The Case for Collaboration

Nurses' Knowledge, Communication Needs, and Future Directions in Neonatal Research

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