Nurse-based secondary preventive follow-up by telephone reduced recurrence of cardiovascular events: a randomised controlled trial

Irewall, Anna-Lotta; Ulvenstam, Anders; Graipe, Anna; Ögren, Joachim; Mooe, Thomas

doi:10.1038/s41598-021-94892-0

Cited by 5 publications

(7 citation statements)

References 33 publications

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“…More than half of the patients in this IS and TIA population were included in a RCT that investigated whether a nurse-led and telephone-based follow-up strategy could decrease MACE in a population after IS, TIA, or acute coronary syndrome. It showed that the intervention improved not only blood pressure and lipid levels 37 , but also decreased recurrence of MACE, suggesting that a structured long-term follow-up of modifiable risk factors could lead to fewer MACE 38 .…”

Section: Discussionmentioning

confidence: 98%

Long-term risk of major adverse cardiovascular events following ischemic stroke or TIA

Carlsson

Irewall

Graipe

et al. 2023

Sci Rep

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Data are scarce on long-term outcomes after ischemic stroke (IS) or transient ischemic attack (TIA). In this prospective cohort study, we examined the cumulative incidence of major adverse cardiovascular events (MACE) after IS and TIA using a competing risk model and factors associated with new events using a Cox-proportional hazard regression model. All patients discharged alive from Östersund Hospital with IS or TIA between 2010 and 2013 (n = 1535) were followed until 31 December 2017. The primary endpoint was a composite of IS, type 1 acute myocardial infarction (AMI), and cardiovascular (CV) death. Secondary endpoints were the individual components of the primary endpoint, in all patients and separated in IS and TIA subgroups. The cumulative incidence of MACE (median follow-up: 4.4 years) was 12.8% (95% CI: 11.2–14.6) within 1 year after discharge and 35.6% (95% CI: 31.8–39.4) by the end of follow-up. The risk of MACE and CV death was significantly increased in IS compared to TIA (p-values < 0.05), but not the risk of IS or type 1 AMI. Age, kidney failure, prior IS, prior AMI, congestive heart failure, atrial fibrillation, and impaired functional status, were associated with an increased risk of MACE. The risk of recurring events after IS and TIA is high. IS patients have a higher risk of MACE and CV death than TIA patients.

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Section: Discussionmentioning

confidence: 98%

Long-term risk of major adverse cardiovascular events following ischemic stroke or TIA

Carlsson

Irewall

Graipe

et al. 2023

Sci Rep

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“…The importance of antiplatelet and lipid-lowering therapy has been widely discussed, together with the importance of maintaining a healthy lifestyle is also essential ( 30 ). Excluding the integrated care approach, regular follow-up of TIA patients could reduce the recurrence of cardiovascular events ( 31 ).…”

Section: Discussionmentioning

confidence: 99%

Transient ischemic attack and coronary artery disease: a two-sample Mendelian randomization analysis

Qi,

Wang,

Qiu

et al. 2023

Front. Cardiovasc. Med.

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BackgroundAlthough observational studies have shown that patients who experienced transient ischemic attacks (TIAs) had a higher risk of coronary artery disease (CAD), the causal relationship is ambiguous.MethodsWe conducted a two-sample Mendelian randomization (MR) study to analyze the causal relationship between TIA and CAD using data from the FinnGen genome-wide association study. Analysis was performed using the inverse-variance weighted (IVW) method. The robustness of the results was evaluated using MR-Egger regression, the weighted median, MR pleiotropy residual sum, and outlier (MR-PRESSO) and multivariable MR analysis.ResultsResults from IVW random-effect model showed that TIA was associated with an increased risk of coronary artery atherosclerosis (OR 1.17, 95% CI 1.06–1.28, P = 0.002), ischemic heart disease (OR 1.15, 95% CI 1.04–1.27, P = 0.007), and myocardial infarction (OR1.15, 95% CI 1.02–1.29, P = 0.025). In addition, heterogeneity and horizontal pleiotropy were observed in the ischemic heart disease results, while the sensitivity analysis revealed no evidence of horizontal pleiotropy in other outcomes.ConclusionsThis MR study demonstrated a potential causal relationship between TIA and CAD. Further research should be conducted to investigate the mechanism underlying the association.

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“…Telephone follow-up is a widely used follow-up method [ 12 ] that enables discharged patients to receive health guidance and medical services related to their disease at home and reduces the recurrence of cardiovascular events during long-term follow-up. [ 1 ] It is well known that Chinese doctors are often overwhelmed by overwork and do not have the time and energy to carefully instruct each patient on medication use. Clinical pharmacists can compensate for this deficiency, which can not only reduce the burden on doctors but also solve the problems of patients in the follow-up process and meet the needs of patients.…”

Section: Discussionmentioning

confidence: 99%

“…Peptic ulcer is a chronic disease; its development and prognosis are closely associated with patient awareness of the disease and treatment compliance, and family treatment after discharge is associated with the treatment effect. A study by Thomas Mooe et al [ 1 ] showed that nurse-based secondary preventive follow-up by telephone reduced the recurrence of cardiovascular events. Several studies on hypertension, diabetes, heart failure, rheumatoid arthritis, and cancer have also demonstrated the benefit of telephone follow-ups in these patients.…”

Section: Introductionmentioning

confidence: 99%

Telephone follow-up by clinical pharmacists can improve treatment outcomes in patients with peptic ulcers: A prospective randomized study

Weng

Chen

et al. 2022

Medicine

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Objective: The purpose of this study was to investigate the effect of pharmaceutical care by clinical pharmacists through telephone follow-up on the treatment outcomes in patients with peptic ulcers who had been discharged from the hospital. Methods: A total of 120 patients with peptic ulcers discharged from the hospital were randomly divided into an intervention group and a control group, with 60 patients in each group. The patients in the two groups received different services. Results: A total of 108 patients with peptic ulcers were enrolled in this study, including 53 in the intervention group and 55 in the control group. This study showed that the Helicobacter pylori eradication rate (19/23, 82.61% vs 13/29, 44.83%), awareness of peptic ulcer disease, medication compliance, diet compliance, and life compliance in the patients in the intervention group were higher than those in the patients in the control group. The H pylori eradication group had higher follow-up scores than the noneradication group. Sex and body mass index (BMI) did not affect the results in either group, but age did. In the control group, younger patients scored higher than older patients, whereas in the intervention group, this difference disappeared for diet compliance and life compliance, and significant differences remained for awareness of basic knowledge regarding peptic ulcer (AOKPU) and medication compliance. Conclusion: As a form of clinical pharmaceutical care, telephone follow-up by clinical pharmacists is recommended for discharged patients with peptic ulcers because it can improve treatment outcomes after discharge.

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Nurse-based secondary preventive follow-up by telephone reduced recurrence of cardiovascular events: a randomised controlled trial

Cited by 5 publications

References 33 publications

Long-term risk of major adverse cardiovascular events following ischemic stroke or TIA

Long-term risk of major adverse cardiovascular events following ischemic stroke or TIA

Transient ischemic attack and coronary artery disease: a two-sample Mendelian randomization analysis

Telephone follow-up by clinical pharmacists can improve treatment outcomes in patients with peptic ulcers: A prospective randomized study

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