Numerical study of red blood cell motion and deformation through a michrochannel using lattice Boltzmann-immersed boundary method

Ghafouri, Ashkan; Hassanzadeh, Amir

doi:10.1007/s40430-016-0604-9

Cited by 8 publications

(7 citation statements)

References 30 publications

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“…It rotates clockwise and preserves its shape. The above observations are well consistent with the findings of previous studies [ 7 , 9 , 26 , 27 , 35 ].…”

Section: Simulation Results and Discussionsupporting

confidence: 94%

“…Three different boundary conditions were implemented in this study. A periodic boundary condition was applied to both the vessel inlet and outlet [ 1 , 4 , 18 , 23 , 29 ]; a nonslip boundary condition was applied to the solid-wall boundary of the vessel [ 7 ]; and a half-way bounce-back boundary condition was applied to the straight vessel walls.…”

Section: Governing Equations and Numerical Methodsmentioning

confidence: 99%

“…An adult RBC has a biconcave shape of diameter 6 μ m and thickness 2 μ m [ 1 – 6 ]. The RBC membrane is highly deformable, which enables the passage of RBCs through a blood vessel with a diameter smaller than that of the RBCs [ 7 , 8 ]. The flow of RBCs through a blood vessel represents a typical fluid-structure interaction (FSI) problem, involving a complex interplay of fluid dynamics, elastic body, and a moving boundary [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

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Numerical Simulations of the Motion and Deformation of Three RBCs during Poiseuille Flow through a Constricted Vessel Using IB-LBM

Wang

Wei

et al. 2018

Computational and Mathematical Methods in Medicine

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The immersed boundary-lattice Boltzmann method (IB-LBM) was used to examine the motion and deformation of three elastic red blood cells (RBCs) during Poiseuille flow through constricted microchannels. The objective was to determine the effects of the degree of constriction and the Reynolds (Re) number of the flow on the physical characteristics of the RBCs. It was found that, with decreasing constriction ratio, the RBCs experienced greater forced deformation as they squeezed through the constriction area compared to at other parts of the microchannel. It was also observed that a longer time was required for the RBCs to squeeze through a narrower constriction. The RBCs subsequently regained a stable shape and gradually migrated toward the centerline of the flow beyond the constriction area. However, a sick RBC was observed to be incapable of passing through a constricted vessel with a constriction ratio ≤1/3 for Re numbers below 0.40.

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“…It rotates clockwise and preserves its shape. The above observations are well consistent with the findings of previous studies [ 7 , 9 , 26 , 27 , 35 ].…”

Section: Simulation Results and Discussionsupporting

confidence: 94%

Section: Governing Equations and Numerical Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Numerical Simulations of the Motion and Deformation of Three RBCs during Poiseuille Flow through a Constricted Vessel Using IB-LBM

Wang

Wei

et al. 2018

Computational and Mathematical Methods in Medicine

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show abstract

“…In the present work, the IIM can be used to simulate the motion and deformation of RBCs in the blood flow. In this study, the initial shape of the RBC is assumed to be a circle with the coordinates given as [1]:…”

Section: Motion Of a Single Membrane In A Simple Channelmentioning

confidence: 99%

“…In this approach, the flow equations are discretized on a curvilinear grid that conforms to the immersed boundary so that the boundary conditions can be enforced easily. However, this method requires robust grid generation to account for the complexity of the immersed boundaries, and the computational cost and memory requirements of these methods are generally high [1].…”

Section: Introductionmentioning

confidence: 99%

Numerical simulation of solid and elastic circular membrane in a simple and dilate microchannel in low Reynolds numbers flows

Mostafavinia

Mirzaee

Pourmahmoud

2017

J Braz. Soc. Mech. Sci. Eng.

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A lattice Boltzmann method to simulate combined radiation–force convection heat transfer mode

Hosseini

Rashidi

Esfahani

2017

J Braz. Soc. Mech. Sci. Eng.

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G ∧ Dimensionless incident radiation H Channel height (m) I Radiation intensity (W m −2 sr −1) k Thermal conductivity (W m −1 K −1) M Total number of discrete lattice direction N Conduction parameter (-) n Outer unit vector normal (-) P Pressure (Pa) P f Scattering phase function Pe Peclet number (-) Pr Prandtl number (-) q r Dimensionless radiative heat flux (-) RP Radiation parameter (-) Re Reynolds number (-) r Position vector (m) s Geometric distance (1/s) t Time (s) T Temperature (K) u Length velocity (m s −1) U Dimensionless × velocity (-) v Height velocity (m s −1) V Dimensionless y velocity (-) w Weight coefficient (-) x Position (m) X Dimensionless coordinate (-) y Position (m) Y Dimensionless coordinate (-) Greek symbols α Thermal diffusivity coefficient (m 2 s −1) β Extinction coefficient (m −1) t Lattice time step (-) x Mesh spacing (-) γ Polar angle (rad) δ Azimuthal angle (rad)

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Numerical study of red blood cell motion and deformation through a michrochannel using lattice Boltzmann-immersed boundary method

Cited by 8 publications

References 30 publications

Numerical Simulations of the Motion and Deformation of Three RBCs during Poiseuille Flow through a Constricted Vessel Using IB-LBM

Numerical Simulations of the Motion and Deformation of Three RBCs during Poiseuille Flow through a Constricted Vessel Using IB-LBM

Numerical simulation of solid and elastic circular membrane in a simple and dilate microchannel in low Reynolds numbers flows

A lattice Boltzmann method to simulate combined radiation–force convection heat transfer mode

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