“…Due to limitation of computing facilities, early research of this kind concentrated on the steady or unsteady flow in aortic and mitral valves in peak systolic phase (Bluestein and Einav, 1994;Huang et al, 1994;Shim and Chang, 1997;Underwood, 1975). As more powerful computers became available, some researchers began to target modelling the moving valve leaflet and blood-leaflet interaction (Kiris et al, 1997;Makhijani et al, 1996aMakhijani et al, ,b, 1997Shi et al, 2003;De Hart et al, 2000, 2003a, 2003bLai et al, 2002).Limitations in computing resources and numerical methods greatly restricted these attempts.…”