Numerical simulation of transapical off-pump mitral valve repair with neochordae implantation

Abstract

The presented results can improve the understanding of the effects of transapical MV repair.

Transapical mitral valve repair with neochordae implantation: FSI analysis of neochordae number and complexity of leaflet prolapse

“…To date, our knowledge of transapical neochordae mechanics has previously relied upon few in vivo animal and human models, 6,50 as well as on MV FE models that did not consider the blood-tissue interaction. 13,14 Because of inherent procedural difficulties in the experimental setup while avoiding interference with normal valve dynamics, or because of limitations in the computational capabilities, these studies have been unable to assess the mechanical interdependence between the neochordae and the LV valve complex through the entire cardiac cycle. Up to now, it remained unclear how neochordae forces were distributed when sutures were anchored to the LV apex instead of the PM tips.…”

Numerical modeling of transapical mitral valve repair

“…The main results of this thesis were published in 4 scientific papers: two articles in journals with impact factor indexed in Clarivate Analytics Web of Science database (Gaidulis et al 2018a;2019), one article in journal indexed in other international databases (Gaidulis et al 2018b) and one paper in international conference proceedings (Romashov et al 2016). These results were presented at 7 international conferences:  40th International Conference "SOLMECH 2016", held in Warsaw (Poland) on August 29 -September 2, 2016.…”

“…Parts of this chapter are published in Gaidulis et al (2018a;2018b;2019) and Romashov et al (2016). The heart is a muscular organ located inside the thoracic cavity, medial to the lungs and posterior to the sternum.…”

“…Virtual transapical MV repair technique is presented, followed by a dynamic FE simulation of MV systolic function before and after virtual repair. Parts of this chapter are published in Gaidulis et al (2018a;2018b;2019) and Romashov et al (2016).…”

“…The parameters calculated during MV systolic function simulations before and after virtual repair for both MV models are presented and evaluated, comparing them with computational results and critical values found in the literature, as well as with post-operative echocardiographic images. Parts of this chapter are published in Gaidulis et al (2018a;2018b;2019) and Romashov et al (2016).…”