Numerical simulation of thermal damage in atherosclerotic plaque using microwave

Abstract

The purpose of this study is to explore the thermal damage of microwave to atherosclerotic plaques in order to achieve the purpose of treating atherosclerosis. In this paper, a fluid-solid-heat coupling model of thermal ablation of atherosclerotic plaque is established (The coupling model of blood-plaque-electromagnetic wave is studied in this paper, in which the thermal ablation of atherosclerotic plaque means that the electromagnetic wave is used to generate heat, and the temperature of atherosclerotic plaque tissue rises. If the cells in it reach the threshold of death temperature, they will be killed, so as to achieve the purpose of thermal ablation.). The electromagnetic field and bio-thermal equation are solved and analyzed by finite element method. By calculating the temperature and thermal damage distribution of microwave on atherosclerotic plaque, the effect of microwave on thermal ablation of atherosclerotic plaque was evaluated. The results show that the thermal damage degree of atherosclerotic plaque is positively correlated with electromagnetic wave frequency, electromagnetic wave power and heating time. The model shows that electromagnetic wave hyperthermia may provide a new therapeutic mode for thermal ablation of atherosclerotic plaques.