As one of the most intriguing wake patterns of two side-by-side circular cylinders at an intermediate gap spacing, the flip-flopping (FF) flow has attracted great attention of fundamental research interest. This FF flow is featured by the intermittently and randomly switching gap flow together with the alternating increase and decrease of mean drag and fluctuating lift forces of the two cylinders. In the literature, there exists a gap of understanding between the low (laminar) and high (turbulent) Reynolds number FF flows, including the flip-over time interval and opinions on the origin of the flow instability. In this paper, we first present a partition map of the wake patterns behind two side-by-side circular cylinders and briefly introduce intrinsic features of each flow pattern. Then, we focus on the FF flow with an aim to explain three fundamental fluid mechanics principles: (i) the origin of the FF flow between laminar and turbulent regimes, (ii) their connections in different flow regimes, and (iii) mechanisms of the significantly varying flip-over time scale of the FF flows. In the laminar regime, we further divide the FF flow into the sub-classed I (FF1) and II (FF2), based on their different origins from the in-phase and anti-phase synchronized vortex shedding instabilities, respectively. By exploring the vortex interactions, we show that the FF flow in the turbulent regime has the same origin and similar vortex dynamics as the FF2 wake in the laminar regime, in spite of some minor disparities in the vortex merging and pairing. Thus, a connection between the FF2 pattern in the laminar flow and the FF pattern in the turbulent flow is established. It is further found that, for the FF flow in the laminar regime (Re < 150 − 200), the mildly decreasing switching time, being several vortex shedding periods, with the increasing Re arises from the growing vortex strength and shrinking vortex formation length. However, for the FF flow in the weak turbulence regime (150 − 200 < Re < 1000 − 1700), the switching time scale increases significantly with Re owing to the increased vortex formation length, enhanced energy dissipation, and intensified spanwise dislocation. The FF in the strong turbulence regime (Re > 1000 − 1700) has a switching time scale of several orders of magnitude longer than the vortex shedding period, where the switching scale decreases gradually with Re due to the stronger Kelvin-Helmholtz vortices, shorter vortex formation length, and wider turbulent wake.