Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application

Esmailidastjerdipour, Parisa; Shahshahani, Fatemeh

doi:10.1007/s11220-022-00409-y

Cited by 15 publications

(3 citation statements)

References 44 publications

(44 reference statements)

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“…Among these available biosensing techniques, optical biosensors have the advantages of high sensitivity, good specificity, easy operation, fast response, portability, and compatibility with optoelectronic integration. To illustrate the advantages, optical biosensors based on waveguides [15], ring resonators [16], resonant microcavities [17], photonic crystals [18], optic fibers [19], Surface Plasmon Resonance (SPR) [20], Localized Surface Plasmon Resonance (LSPR) [21], and Surface Enhanced Raman Spectroscopy (SERS) [22], have been proposed as effective detectors of various kinds of bio species, such as and biomarkers, proteins, DNAs, virus, bacterium, and cells. On the other hand, from the material perspective of biosensing technology, porous silicon (PSi) is a versatile nanoscale material for biosensing applications.…”

Section: Positive Results May Not Mean Persistent Infectionmentioning

confidence: 99%

Optical Biosensor Based on Porous Silicon and Tamm Plasmon Polariton for Detection of CagA Antigen of <em>Helicobacter Pylori</em>

Rong,

Kavokin,

Sawan

2024

Preprint

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Helicobacter Pylori (H. Pylori) is a common pathogen with high prevalence of infection in human populations. Diagnosis of H. Pylori infection is critical for its treatment, eradication, and prognosis. Biosensors have been demonstrated to be powerful for rapid onsite detection of pathogens, particularly for point-of-care test (POCT) scenarios. In this work, we propose a novel optical biosensor, based on nanomaterial porous silicon (PSi) and photonic surface state Tamm Plasmon Polariton (TPP), for detection of cytotoxin-associated antigen A (CagA) antigen of H. Pylori bacterium. We fabricated the PSi TPP biosensor, analysed its optical characteristics and demonstrated through experiments towards sensing of CagA antigen, that TPP biosensor has sensitivity of 100 pm/(ng/ml), limit of detection of 0.01 ng/ml, and specificity in terms of positive-to-negative ratio of more than six. From these performance factors, it can be concluded that TPP biosensor can serve as an effective tool for diagnosis of H. Pylori infection, either in analytical labs or in POCT applications.

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Section: Positive Results May Not Mean Persistent Infectionmentioning

confidence: 99%

Optical Biosensor Based on Porous Silicon and Tamm Plasmon Polariton for Detection of CagA Antigen of <em>Helicobacter Pylori</em>

Rong,

Kavokin,

Sawan

2024

Preprint

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“…Graphene conductivity or σ g (ω, μ C , Γ, Τ) is one of the most effective factors in describing graphene. Which is described like this [46][47][48][49][50]:…”

Section: Graphene Conductivitymentioning

confidence: 99%

Implementation of a Graphene-Based RGW Coupler for THz Applications

Kiani

Hamedani

Rezaei

2023

Preprint

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Ridge gap waveguide is one of the new technologies in the field of waveguides. Their advantages include being planar, low cost of construction, shielding by metal without the need for problems related to packaging, the formation of a narrow gap enclosed between two metal plates, realization of the texture on one of the metal plates and lower losses. These structures have no mechanical connection. While electric currents must flow in them. In this article, two graphene-based ridge gap waveguide coupler structures are presented. The designed structures are used in the THz band. By using graphene in the THz frequency band, frequency reconfigurable can be achieved. S-parameters curves, phase difference diagrams and e-field distributions are reported for two graphene-based ridge gap waveguide couplers.

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“…In particular, once the sensor construction is complex, the calculation is become very cumbersome and its need to long time. So, it is important to find a simple and non-complex method for analyzing parameters smoothly [27][28][29][30]. Different methods are used for modeling and simulation optical fiber sensors based SPR such as, expansion and propagation method [31], and multilayer structure transfer matrix modeling [32,33].…”

Section: Introductionmentioning

confidence: 99%

Structure Design and Sensitivity Optimization of Optical Fiber Biosensor Based Au Nano Column - TiO2 Heterostructure

Younus,

Ameen,

Salih

2024

Trends Sci

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An investigation on a single mode optical fiber sensor-based surface plasmon resonance was carried out in this work. A titanium dioxide (TiO2) coated gold Nano-column (Au) are deposited on the proposed sensor and theoretically analyzed using COMSOL Muliphysics software 5.3. Presence of TiO2 over the Au Nano-column can improve the sensitivity of the sensor and tune the resonance peak of transmission spectrum from visible region to near-infrared region. The size effect of TiO2 nanoparticles on the sensor performance is studied. The optimum parameters of such as Au size and separation width between the Au Nano-column have been selected to enhance the performance of the sensor. In comparison, the sensor with TiO2 over Au Nano-column is significantly improve the sensitivity and develop the sensor performance. The greater sensitivity of 5243.76 nm/RIU (refractive index unit) is obtained of sensor with TiO2 over Au Nano-column when the external refractive index of analyte is varying from 1.33 to 1.39, while sensitivity of the sensor coated with Au Nano-column is obtained to be 4643.17 nm/RIU for the same analyte range. Above results can be used to predict the best parameters values of the sensor that corresponding to the greatest sensitivities of detection and finally opening new study in the field of gas sensors. HIGHLIGHTS Optical fiber biosensors are a devices that use to measure the analyte by using the optical field Optical fiber biosensors have a high detection speed and low-cost, compared to congenital sensors The optical fiber sensors based SPR are widely used for biosensor applications The novelty in this research is the fabricate of optical fiber sensor coated with TiO2 over Au Nano-column based SPR foe gas detection GRAPHICAL ABSTRACT

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Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application

Cited by 15 publications

References 44 publications

Optical Biosensor Based on Porous Silicon and Tamm Plasmon Polariton for Detection of CagA Antigen of <em>Helicobacter Pylori</em>

Optical Biosensor Based on Porous Silicon and Tamm Plasmon Polariton for Detection of CagA Antigen of <em>Helicobacter Pylori</em>

Implementation of a Graphene-Based RGW Coupler for THz Applications

Structure Design and Sensitivity Optimization of Optical Fiber Biosensor Based Au Nano Column - TiO2 Heterostructure

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