Numerical Simulation of Blood Flow in Double-Barreled Cannon EVAR and its Clinical Validation

Kan, Tainsong Chen ChungDann

doi:10.4172/2329-6925.1000160

Cited by 3 publications

(1 citation statement)

References 15 publications

(39 reference statements)

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“…Furthermore, an assumption of flow in aorta with > 0.5 mm diameter as a Newtonian is acceptable since the viscosity of blood is comparatively constant at the high shear rates (100/s), and this case is typically found in abdominal aortas [40,41]. For the fluid domain, the flow of blood in vessels and arteries are pulsatile [42]. Thus, a user-defined function (UDF) for a pulsatile velocity profile was used at the inlet for the whole cardiac pulse cycle with a velocity magnitude between 0 and 0.3 m/s as shown in Fig.…”

Section: Boundary Conditions and Materials Propertiesmentioning

confidence: 99%

Computational study on hemodynamic changes in patient-specific proximal neck angulation of abdominal aortic aneurysm with time-varying velocity

Algabri

Rookkapan

Gramigna

et al. 2019

Australas Phys Eng Sci Med

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Aneurysms are considered as a critical cardiovascular disease worldwide when they rupture. The clinical understanding of geometrical impact on the flow behaviour and biomechanics of abdominal aortic aneurysm (AAA) is progressively developing. Proximal neck angulations of AAAs are believed to influence the hemodynamic changes and wall shear stress (WSS) within AAAs. Our aim was to perform pulsatile simulations using computational fluid dynamics (CFD) for patient-specific geometry to investigate the influence of severe angular (≥ 60) neck on AAA's hemodynamic and wall shear stress. The patient's geometrical characteristics were obtained from a computed tomography images database of AAA patients. The AAA geometry was reconstructed using Mimics software. In computational method, blood was assumed Newtonian fluid and an inlet varying velocity waveform in a cardiac cycle was assigned. The CFD study was performed with ANSYS software. The results of flow behaviours indicated that the blood flow through severe bending of angular neck leads to high turbulence and asymmetry of flows within the aneurysm sac resulting in blood recirculation. The high wall shear stress (WSS) occurred near the AAA neck and on surface of aneurysm sac. This study explained and showed flow behaviours and WSS progression within high angular neck AAA and risk prediction of abdominal aorta rupture. We expect that the visualization of blood flow and hemodynamic changes resulted from CFD simulation could be as an extra tool to assist clinicians during a decision making when estimation the risks of interventional procedures.

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Section: Boundary Conditions and Materials Propertiesmentioning

confidence: 99%

Computational study on hemodynamic changes in patient-specific proximal neck angulation of abdominal aortic aneurysm with time-varying velocity

Algabri

Rookkapan

Gramigna

et al. 2019

Australas Phys Eng Sci Med

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Visualization of Blood Flow in AAA Patient-Specific Geometry: 3-D Reconstruction and Simulation Procedures

2019

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Computational Study of Abdominal Aortic Aneurysms with Severely Angulated Neck Based on Transient Hemodynamics Using an Idealized Model

et al. 2022

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An abdominal aortic aneurysm (AAA) is an enlargement of the abdominal aorta that can become a life-threatening disease. The pulsatile blood flow exhibits intricate laminar patterns in the abdominal portion of the human aorta under normal resting conditions, whereas secondary flows are caused by adjacent branches and abnormal vessel geometries. If a pathological disorder (e.g., aneurysm) alters the structural composition of the artery wall, the flow dynamics become more complex. In this study, we analyzed the hemodynamics of pulsatile blood flow in three-dimensional AAA models. Computational predictions of hemodynamic changes were performed considering idealized models for four severe proximal neck angulations of symmetric aneurysms assuming conditions of laminar flow and a rigid artery wall. The predictions were based on computational fluid dynamics throughout the cardiac cycle. Postprocessing was used to visualize the numerical findings. The hemodynamic changes in factors such as velocity, flow streamline, pressure, and wall shear stress were obtained and visualized. The resulting blood flow through the severely angulated proximal neck of the abdominal aorta caused strong turbulence and asymmetric flow inside the aneurysm sac, leading to blood recirculation, especially during diastole. The simulation results showed the formation of regions with high and low wall shear stress, turbulent flow, and recirculation in the aneurysm sac depending on the angulation, which could have led to aortic wall weakness.

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Numerical Simulation of Blood Flow in Double-Barreled Cannon EVAR and its Clinical Validation

Cited by 3 publications

References 15 publications

Computational study on hemodynamic changes in patient-specific proximal neck angulation of abdominal aortic aneurysm with time-varying velocity

Computational study on hemodynamic changes in patient-specific proximal neck angulation of abdominal aortic aneurysm with time-varying velocity

Visualization of Blood Flow in AAA Patient-Specific Geometry: 3-D Reconstruction and Simulation Procedures

Computational Study of Abdominal Aortic Aneurysms with Severely Angulated Neck Based on Transient Hemodynamics Using an Idealized Model

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