Numerical Modelling of Blood flow Behaviour in the Valved Catheter of the PUCA-Pump, a LVAD

Morsink, Peter; Verkerke, G.J.; Grootenboer, H.J.; Mihaylov, D; Rakhorst, Gerhard

doi:10.1177/039139889702000508

Cited by 8 publications

(4 citation statements)

References 9 publications

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“…When considering the pressure losses in the numerical simulation of catheter configuration A, the pressure losses of the valves appeared to be twice as high as from the catheter itself. New valve designs are under construction (18) to decrease pressure losses. As a result, smaller catheters can be applied.…”

Section: Discussionmentioning

confidence: 99%

Numerical Simulation of the Pulsating Catheter Pump: A Left Ventricular Assist Device

Verkerke¹,

Mihaylov

Geertsema

et al. 1999

Artificial Organs

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The pulsating catheter (PUCA) pump, a left ventricular assist device, consists of a hydraulically or pneumatically driven membrane pump, extracorporeally placed and mounted to a valved catheter. The catheter is introduced into an easily accessible artery and positioned with its distal tip in the left ventricle. Blood is aspirated from the left ventricle during systole and ejected into the ascending aorta during diastole. A numerical model of the PUCA pump has been developed to determine the internal diameter of the PUCA pump catheter that allows a certain blood flow. The model considers a limitation of mechanical blood damage and determines the accompanying pressure and flow profile for driving the pump. For a flow of 5 L/min, a catheter with an internal diameter of at least 6. 95 mm is required. For 3 L/min, the minimal diameter is 5.50 mm. The latter catheter can be introduced in the axillary artery, the former via the aorta during an open thorax surgical procedure. To validate the numerical model, 2 different PUCA pump configurations were tested in vitro. Results showed a good resemblance between model and in vitro behavior of the PUCA pump.

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Section: Discussionmentioning

confidence: 99%

Numerical Simulation of the Pulsating Catheter Pump: A Left Ventricular Assist Device

Verkerke¹,

Mihaylov

Geertsema

et al. 1999

Artificial Organs

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“…It has been shown that the occurrence of haemolysis by shear stress depends not only on the shear stress level but also on the duration of the shear stress. 24,25 Studies have shown that blood is transported in a laminar flow in all vessels throughout the human body. The highest measured speed is 1,175 mm/s in the femoral artery with a diameter of 5 mm.…”

Section: Resistance Of Erythrocytesmentioning

confidence: 99%

Haemolysis induced by mechanical circulatory support devices: unsolved problems

Köhne

2020

Perfusion

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Since the use of continuous flow blood pumps as ventricular assist devices is standard, the problems with haemolysis have increased. It is mainly induced by shear stress affecting the erythrocyte membrane. There are many investigations about haemolysis in laminar and turbulent blood flow. The results defined as threshold levels for the damage of erythrocytes depend on the exposure time of the shear stress, but they are very different, depending on the used experimental methods or the calculation strategy. Here, the results are resumed and shown in curves. Different models for the calculation of the strengths of erythrocytes are discussed. There are few results reported about tests of haemolysis in blood pumps, but some theoretical approaches for the design of continuous flow blood pumps according to low haemolysis have been investigated within the last years.

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“…By means of a guiding catheter, the tip of the catheter is introduced via peripheral arteries or open thorax into the left ventricle. The pump aspirates at least 3 L/min blood from the left ventricle and ejects it into the aorta (Morsink et al, 1997). The PUCA pump has a pneumatic driving system, which is electrocardiogram-triggered.…”

Section: The Puca-pump Project: a Case Studymentioning

confidence: 99%

The effects of team expert choice on group decision-making in collaborative new product development: a pilot study

Hummel

Rossum

Verkerke

et al. 2000

J. Multi-Crit. Decis. Anal.

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This study analyses the effects of Team Expert Choice on group decision-making in collaborative new product development. We applied Team Expert Choice to support a product evaluation conducted by a new product development group composed of professionally diverse members. The evaluation resulted in valuable guidelines for improving the development and diffusion of the product. According to the evaluators, Team Expert Choice enhanced task processes, social processes, task outcomes and social outcomes of this product evaluation. In this context of collaborative new product development, Team Expert Choice proved to be an appropriate tool for group decision-making.

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Numerical Modelling of Blood flow Behaviour in the Valved Catheter of the PUCA-Pump, a LVAD

Cited by 8 publications

References 9 publications

Numerical Simulation of the Pulsating Catheter Pump: A Left Ventricular Assist Device

Numerical Simulation of the Pulsating Catheter Pump: A Left Ventricular Assist Device

Haemolysis induced by mechanical circulatory support devices: unsolved problems

The effects of team expert choice on group decision-making in collaborative new product development: a pilot study

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