Numerical Modeling of Glucose Biosensor With pH-Based Electrochemical Field-Effect Transistor Device

Abstract

In this work, we present a new model for glucose detection using an Electrochemical Field Effect Transistor (ElecFET) with a MATLAB TM software. ElecFET is a device in which the basic element is a pH-ChemFET (pHsensitive Chemical Field Effect Transistor) designed with an integrated platinum microelectrode around the sensitive gate dielectric capable to trigger electrochemical reactions. A number of parameters such as polarization time (T pol) and polarization voltage (Vp) have been investigated, as well as the enzymatic unit number per volume (Nenz), the Michaelis constant (K M) and the glucose concentration (C 0). Each of the aforementioned parameters influences the glucose sensor response. Experimental data compared with our numerical model showed a reasonable fit.

Development of Rapid Dispense-Printed Flexible Interdigitated Electrode Modified with rGO-TiO2 Nanohybrid for Glucose Detection

“…1 below which governs the rate of enzymatic reaction (R) occurs in the solution phase above the electrode has been previously discussed and used by other researchers for many sensing applications. [51][52][53] Herewith, the parameter C glucose is the varied glucose concentration, while K m is a characteristic Michaelis-Menten coefficient which is defined as 0.5 mmol L −1 . For electric field analysis, the electric currents in layered shells under AC/DC module had been used by defining electrical conductivity of silver as 6.3e7 S m −1 .…”