We demonstrate control of the collapse and expansion of an 88 Sr Bose-Einstein condensate using an optical Feshbach resonance (OFR) near the 1 S0-3 P1 intercombination transition at 689 nm. Significant changes in dynamics are caused by modifications of scattering length by up to ±10 a bg , where the background scattering length of 88 Sr is a bg = −2 a0 (1 a0 = 0.053 nm). Changes in scattering length are monitored through changes in the size of the condensate after a time-of-flight measurement. Because the background scattering length is close to zero, blue detuning of the OFR laser with respect to a photoassociative resonance leads to increased interaction energy and a faster condensate expansion, while red detuning triggers a collapse of the condensate. The results are modeled with the time-dependent non-linear Gross-Pitaevskii equation.The ability to tune interactions in ultracold atomic gases makes these systems ideal for exploring many-body physics [1] and has enabled some of the most important recent advances in atomic physics, such as investigation of the Bose-Einstein condensate (BEC)-Bardeen-CooperSchrieffer crossover regime [1] and creation of quantum degenerate molecules [2,3]. Magnetic Feshbach resonances [4], which are the standard tool for changing atomic interactions, have proven incredibly powerful, but they are also limited because the methods for creating magnetic fields preclude high-frequency spatial and temporal modulation. Also, in atoms with non-degenerate ground states, such as alkaline-earth-metal atoms, magnetic Feshbach resonances do not exist.These limitations can be overcome by using an optical Feshbach resonance (OFR), which tunes interatomic interactions by coupling a colliding atom pair to a bound molecular level of an excited state potential with a laser tuned near a photoassociative resonance [5]. Optical Feshbach resonances may open new avenues of research in nonlinear matter waves [6][7][8] and quantum fluids [9][10][11], and could be very valuable for experiments with fermionic alkaline-earth atoms [12,13] Early experiments on OFRs [22-24] used strong dipoleallowed transitions in alkali-metal atoms to alter atomic collision properties, but substantial change in the atomatom scattering length was accompanied by rapid atom losses. Tuning of interactions in alkali-metal atoms, but with smaller atom loss, was recently obtained with a magnetic Feshbach resonance using an AC Stark shift of the closed channel to modify the position of the resonance [25,26]. Recently, a multiple-laser optical method was proposed for wider modulation of the interaction strength near a magnetic Feshbach resonance [27]. Unfortunately, none of these hybrid variations are feasible for atoms lacking magnetic Feshbach resonances.Ciurylo et al. [28,29] predicted that an OFR induced by a laser tuned near a weakly allowed transition should tune the scattering length with significantly less induced losses. This can be done with divalent atoms, such as strontium and ytterbium, by exciting near an intercombinatio...