Numerical method to measure velocity integration, stroke volume and cardiac output while rest: using 2D fluid-solid interaction model

Abstract

Development of knowledge of cardiovascular diseases and treatments strongly depends on understanding of hemodynamic measurements. Hemodynamic parameters, therefore, have been investigated using simulation-based methods. A two-dimensional model was applied for seven healthy subjects with echo-Doppler at rest. Echocardiography imaging was also utilized to gain the geometry of the aortic valve. Fluid-Structure Interaction (FSI) model was carried out, coupling an Arbitrary Lagrangian-Eulerian mesh. Pressure loads were used as boundary conditions on the valve's ventricular and aortic sides. Pressure loads used were the calculated brachial pressures plus differences between brachial, central and left ventricular pressures. The FSI model predicted the velocity integration, stroke volume and cardiac output over a range of heart rates while rest. Numerical results generally had a difference of 5.4 to 15.87% with Doppler results. Linear correlations between numerical and clinical approaches have been applied. This makes possible predictions achieved from the FSI model to be gained which are highly accurate (e.g. correlation factor r = 0.995, 0.990 and 0.990 for velocity integration, stroke volume and cardiac output, respectively). The obtained numerical results showed that numerical methods can be combined with clinical measurements to provide good estimates of patient specific hemodynamics for different subjects.

Finite element analysis of fibre-reinforced constitutive formulation of Cadisc-L

“…The finite element method is widely used for strain and stress analysis of engineering structures particularly in biomechanics and proved to be very functional for complex models of living tissues structures (Amerian et al, 2014;Bahraseman et al, 2013Bahraseman et al, , 2014aBahraseman et al, , 2014bBahraseman et al, , 2015Bahraseman et al, & 2016Dietrich et al, 1991;Kedzior et al, 1996;Khosravi et al, 2014aKhosravi et al, & 2014bPoor et al, 2017;Sabooni et al, 2015;Skalli, 1999;Zienkiewicz & Taylor, 1991). These computational tools provide assistance for a better interpretation of clinical and experimental data to improve the prosthesis design.…”

Applied Fluid-Structure Interaction Technique to Initial Insight into the Effect of Exercise on the Aortic Valve Stroke Work

“…Simultaneous simulations of Fluid-Structure Interaction (FSI) have the potential for non-invasive prediction of stroke work. Recently, FSI has been utilized to investigate heart and heart valve mechanics [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] . Studies include use of a twodimensional model to evaluate the stroke volume and cardiac output for a healthy subject [29].…”

Applied Fluid-Structure Interaction Technique to Initial Insight into the Effect of Exercise on the Aortic Valve Stroke Work

“…Recently, FSI has been utilized to investigate heart and heart valve mechanics [19][20][21][22][23][24][25][26][27][28][29][30][31].…”