Numerical investigation of the haemodynamics at a patched arterial bypass anastomosis

Optimal Control and Shape Optimization of Aorto-Coronaric Bypass Anastomoses

“…In general, the flow at the distal junction exhibits considerable spatial and temporal variations. With the adaptation operated by shape optimization technique we find, as already seen, a graft which resembles the Taylor patch configuration in which the anastomotic flow is less disturbed, a less adverse shear stress distribution prevails and furthermore flow separation is reduced 7 . Intimal thickening hyperplasia should be alleviated at the toe in the new bypass configuration proposed.…”

“…Different cuffed models are used such as Taylor Patch 9 and Miller Cuff Bypass 11 , but also standard end-to-side anastomoses at different graft angle 10 or other shaped carbon-fiber prostheses. For a discussion and a comparative approach see Cole et al 8,7 . In the cardiovascular system altered flow conditions such as separation, flow reversal, low and oscillatory shear stress areas and abnormal pulse pattern are all recognized as potentially important factors in the development of arterial diseases (White et al 44 , Loth et al 28 ).…”

Shape optimization for viscous flows by reduced basis methods and free‐form deformation

“…Consequently, different surgery procedures are used to set up a bypass; in general, the connection of the graft to the coronary artery can be done using an end-toside or a side-to-side anastomosis. For a discussion and a comparative approach see, for example, Cole et al [11]. Bypass can be made by organic material (e.g.…”

“…This can have useful clinical applications especially in surgical procedures. Moreover, computational studies have highlighted the correlation between geometrical features (such as anastomotic angle and graft-artery diameter ratio) and vorticity, shear stress, shear stress gradient [25,45] and oscillatory shear index [34], as effect of recirculation, flow separation and moving stagnation zones [11,14]. For the problem at hand, we are interested in the minimization of the blood vorticity in the downfield region of the bypass by changing the shape of the anastomosis.…”

Shape Design in Aorto-Coronaric Bypass Anastomoses Using Perturbation Theory

“…They may feature very different shape for bypass anastomoses, such as, e.g., cuffed arteriovenous access grafts. Different cuffed models are used such as Taylor Patch [2] and Miller Cuff Bypass, [4], but also standard end-to-side anastomoses at different graft angle ( [3]) or other shaped carbon-fiber prostheses. In the cardiovascular system altered flow conditions such as separation, flow reversal, low and oscillatory shear stress areas and abnormal pulse pattern are all recognized as potentially important factors in the development of arterial diseases ( [13] and [15]).…”