Numerical investigation of electrohydrodynamic effect for size-tunable droplet formation in a flow-focusing microfluidic device

Majd, Sara Alizadeh; Zand, Mahdi Moghimi; Javidi, Reza; Rahimian, Mohammad Hassan

doi:10.1080/1539445x.2023.2179069

Cited by 1 publication

(1 citation statement)

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“…This device could produce double emulsion droplets in the temperature range of 0–40 °C with a high monodispersity. Majd et al studied the effect of geometry on droplet production and electric field intensity using a flow-focusing 3D-printed microdevice and DC electric field [ 76 ]. They found that this system was suitable for generating smaller droplets without significantly altering the frequency of droplet formation.…”

Section: Droplet-based Microfluidicsmentioning

confidence: 99%

Droplet-Based Microfluidics: Applications in Pharmaceuticals

Trinh,

Do,

Nam

et al. 2023

Pharmaceuticals

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Droplet-based microfluidics offer great opportunities for applications in various fields, such as diagnostics, food sciences, and drug discovery. A droplet provides an isolated environment for performing a single reaction within a microscale-volume sample, allowing for a fast reaction with a high sensitivity, high throughput, and low risk of cross-contamination. Owing to several remarkable features, droplet-based microfluidic techniques have been intensively studied. In this review, we discuss the impact of droplet microfluidics, particularly focusing on drug screening and development. In addition, we surveyed various methods of device fabrication and droplet generation/manipulation. We further highlight some promising studies covering drug synthesis and delivery that were updated within the last 5 years. This review provides researchers with a quick guide that includes the most up-to-date and relevant information on the latest scientific findings on the development of droplet-based microfluidics in the pharmaceutical field.

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Section: Droplet-based Microfluidicsmentioning

confidence: 99%