Numerical analysis of light elements transport in a unidirectional solidification furnace

Abstract

Extremely high enantioselectivity (>99.5% ee) and chemical yield (>99%) are achieved in an asymmetric autocatalytic reaction. A (5‐pyrimidyl)alkanol with a tert‐butylethynyl group at its 2‐position (1) is a very efficient asymmetric autocatalyst in the enantioselective alkylation in Equation (1).