Numerical analysis of a gas bubble near bio-materials in an ultrasound field

Fong, Siew Wan; Klaseboer, Evert; Turangan, Cary; Khoo, Boo Cheong; Hung, K. C.

doi:10.1016/j.ultrasmedbio.2006.03.005

Cited by 72 publications

(69 citation statements)

References 31 publications

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“…If the wave is strong enough, a high-speed liquid jet forms towards the end of collapse. Axisymmetric jetting for acoustic bubbles in an infinite liquid was studied by Calvisi et al [29], Wang & Blake [30,31], and near a boundary subjected to ultrasound propagating in the direction perpendicular to the boundary by Klaseboer & Khoo [32,33], Fong et al [34,35], Calvisi et al [29,36] and Curtiss et al [17]. Wang & Manmi [37] implemented the three-dimensional boundary integral method (BIM) model for microbubble dynamics subjected to ultrasound propagated parallel to the boundary (figure 11).…”

Section: Ultrasonic Bubbles Near a Wallmentioning

confidence: 99%

Cavitation and bubble dynamics: the Kelvin impulse and its applications

Blake¹,

Leppinen²,

Wang³

2015

Interface Focus.

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Cavitation and bubble dynamics have a wide range of practical applications in a range of disciplines, including hydraulic, mechanical and naval engineering, oil exploration, clinical medicine and sonochemistry. However, this paper focuses on how a fundamental concept, the Kelvin impulse, can provide practical insights into engineering and industrial design problems. The pathway is provided through physical insight, idealized experiments and enhancing the accuracy and interpretation of the computation. In 1966, Benjamin and Ellis made a number of important statements relating to the use of the Kelvin impulse in cavitation and bubble dynamics, one of these being ‘One should always reason in terms of the Kelvin impulse, not in terms of the fluid momentum…’. We revisit part of this paper, developing the Kelvin impulse from first principles, using it, not only as a check on advanced computations (for which it was first used!), but also to provide greater physical insights into cavitation bubble dynamics near boundaries (rigid, potential free surface, two-fluid interface, flexible surface and axisymmetric stagnation point flow) and to provide predictions on different types of bubble collapse behaviour, later compared against experiments. The paper concludes with two recent studies involving (i) the direction of the jet formation in a cavitation bubble close to a rigid boundary in the presence of high-intensity ultrasound propagated parallel to the surface and (ii) the study of a ‘paradigm bubble model’ for the collapse of a translating spherical bubble, sometimes leading to a constant velocity high-speed jet, known as the Longuet-Higgins jet.

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Section: Ultrasonic Bubbles Near a Wallmentioning

confidence: 99%

Cavitation and bubble dynamics: the Kelvin impulse and its applications

Blake¹,

Leppinen²,

Wang³

2015

Interface Focus.

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“…Fong et al have experimentally studied the interaction of a cavitation bubble and adjacent biomaterial in an ultrasound field. They observed that cavitation bubble behaviour is highly sensitive to different types of biomaterial (Fong et al, 2006). They describe the interaction of cavitation bubbles with a range of biomaterials.…”

Section: Cavitationmentioning

confidence: 99%

High-power low-frequency ultrasound: A review of tissue dissection and ablation in medicine and surgery

OʼDaly

Morris

Gavin³

et al. 2008

Journal of Materials Processing Technology

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Ab s t r a c t High-power low-frequency ultrasound in the range 20-60 kHz has wide ranging clinical applications in surgical and medical instruments for biological tissue cutting, ablation or fragmentation, and removal. Despite widespread clinical application and common device operating characteristics, there is an incomplete understanding of the mechanism of tissue failure, removal and damage. The relative contribution of cavitation, direct mechanical impact and thermal effects to each process for specific tissue types remains unclear. Different and distinct mechanisms and rates of tissue removal are observed for interaction with soft and hard tissue types. Device operating parameters known to affect the interaction include frequency, peak-peak tip amplitude, suction and application time. To date, there has been little analysis of the effect of variations in, and interactions of, these parameters on tissue removal and damage for individual biological tissue types. Potential controllable damage mechanisms occurring in tissues include alteration in global biomechanical properties, histomorphological changes, protein denaturation and tissue necrosis. This paper presents a critical review of the literature on the clinical application, mechanism of tissue interaction, removal and residual tissue damage. It describes known mechanisms for distinct tissue types.

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“…[4][5][6][7] Between these two extremes, the translational dynamics of bubbles oscillating near compliant interfaces are much more nuanced and depend on a number of factors. 8,9 With the current expanding interest in using microbubbles to induce therapeutic bioeffects in tissue there has also been interest in the deformation of, and stresses induced within, adjacent tissue due to the bubble motion. Previous experimental studies on the dynamics of cells, lipid membranes, and tissue phantoms in response to the motion of adjacent bubbles have shown that deformation and damage of the materials may occur.…”

Section: Introductionmentioning

confidence: 99%

Model for the dynamics of a spherical bubble undergoing small shape oscillations between parallel soft elastic layers

Hay

Ilinskii

Zabolotskaya

et al. 2013

The Journal of the Acoustical Society of America

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A model is developed for a pulsating and translating gas bubble immersed in liquid in a channel formed by two soft, thin elastic parallel layers having densities equal to that of the surrounding liquid and small, but finite, shear moduli. The bubble is nominally spherical but free to undergo small shape deformations. Shear strain in the elastic layers is estimated in a way which is valid for short, transient excitations of the system. Coupled nonlinear second-order differential equations are obtained for the shape and position of the bubble, and numerical integration of an expression for the liquid velocity at the layer interfaces yields an estimate of the elastic layer displacement. Numerical integration of the dynamical equations reveals behavior consistent with laboratory observations of acoustically excited bubbles in ex vivo vessels reported by Chen et al.

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Numerical analysis of a gas bubble near bio-materials in an ultrasound field

Cited by 72 publications

References 31 publications

Cavitation and bubble dynamics: the Kelvin impulse and its applications

Cavitation and bubble dynamics: the Kelvin impulse and its applications

High-power low-frequency ultrasound: A review of tissue dissection and ablation in medicine and surgery

Model for the dynamics of a spherical bubble undergoing small shape oscillations between parallel soft elastic layers

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