Numbers

Iron therapy for pre-operative anaemia

“…Two review authors (ON and BK) independently assessed each study report for risk of bias by making judgements on the following questions according to the criteria outlined in the Cochrane Handbook for Systematic Reviews of Interventions (Higgins 2011). A third review author (HA) independently assessed risk of bias to ensure agreement.…”

Breastfeeding education and support for women with multiple pregnancies

“…Two review authors (HW, TD or SW) will independently assess risk of bias for each study using the criteria outlined in the Cochrane Handbook for Systematic Reviews of Interventions (Higgins 2011). We will resolve any disagreement by discussion or by involving a third assessor (MR).…”

“…If we identify trials with more than two arms we will pool results using the methods set out in the Handbook (Higgins 2011) to avoid double-counting.…”

Evidence for the use of high flow nasal cannula therapy for respiratory management in paediatric units

“…Any disagreements will be resolved by a third author (FB). We will include a risk of bias table as recommended in the Cochrane Handbook for Systematic Reviews of Interventions (Higgins 2011). The judgements 'low risk', 'high risk' and 'unclear risk' will be used in the table to determine bias.…”

“…We will undertake subgroup analysis to examine possible clinical variability when the I 2 statistic is less than 50% but heterogeneity remains statistically significant. We will analyse outcome data from trial populations rather than individuals in order to explain possible sources of variability ( Higgins 2011). …”