Number of US Physicians Participating in Clinical Research Continuing to Drop (Association of Clinical Research Organizations Survey)

Eastman, Peggy

doi:10.1097/01.cot.0000387258.26621.fd

Cited by 6 publications

(7 citation statements)

References 1 publication

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“…An analysis of 333 randomized controlled trials (RCTs) conducted in the United Kingdom between 1971 and 2000 revealed that just over one-half failed to recruit the desired sample size, one-fifth recruited at least 75% of the target sample, while a further fifth recruited <25% of the planned number of patients 9. It is also worrying that the number of physicians pursuing a career in research has also declined10,11 and ‘physician-scientist’ has now become an ‘endangered species’ 12. There is clearly a need to examine why both physicians and patients are reluctant to take part in clinical research.…”

Section: Introductionmentioning

confidence: 99%

Physician participation in clinical research and trials: issues and approaches

Rahman¹,

Majumder²,

Shaban³

et al. 2011

AMEP

127

148

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The rapid development of new drugs, therapies, and devices has created a dramatic increase in the number of clinical research studies that highlights the need for greater participation in research by physicians as well as patients. Furthermore, the potential of clinical research is unlikely to be reached without greater participation of physicians in research. Physicians face a variety of barriers with regard to participation in clinical research. These barriers are system-or organization-related as well as research-and physician-related. To encourage physician participation, appropriate organizational and operational infrastructures are needed in health care institutes to support research planning and management. All physicians should receive education and training in the fundamentals of research design and methodology, which need to be incorporated into undergraduate medical education and postgraduate training curricula and then reinforced through continuing medical education. Medical schools need to analyze current practices of teaching–learning and research, and reflect upon possible changes needed to develop a ‘student-focused teaching–learning and research culture’. This article examines the barriers to and benefits of physician participation in clinical research as well as interventions needed to increase their participation, including the specific role of undergraduate medical education. The main challenge is the unwillingness of many physicians and patients to participate in clinical trials. Barriers to participation include lack of time, lack of resources, trial-specific issues, communication difficulties, conflicts between the role of clinician and scientist, inadequate research experience and training for physicians, lack of rewards and recognition for physicians, and sometimes a scientifically uninteresting research question, among others. Strategies to encourage physician participation in clinical research include financial and nonfinancial incentives, adequate training, research questions that are in line with physician interests and have clear potential to improve patient care, and regular feedback. Finally, encouraging research culture and fostering the development of inquiry and research-based learning among medical students is now a high priority in order to develop more and better clinician-researchers.

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Section: Introductionmentioning

confidence: 99%

Physician participation in clinical research and trials: issues and approaches

Rahman¹,

Majumder²,

Shaban³

et al. 2011

AMEP

127

148

View full text Add to dashboard Cite

show abstract

“…Key factors cited by physicians as barriers to participation in clinical trials included lack of time and resources . In a survey of US and European physicians, 70% indicated that current regulations make clinical trials difficult to manage . Moreover, in the United Kingdom from 1994 to 2002, fewer than one third of funded studies achieved recruitment targets …”

Section: Discussionmentioning

confidence: 99%

“…Removing barriers to clinical research is equally important. The most commonly reported obstacles in clinical research are insufficient funding, the need for well‐trained clinical investigators, and the lack of enhanced information systems to identify clinical trials and assist physicians in understanding regulatory requirements, liability, and compensation . The European Network of Centers for Pharmacoepidemiology and Pharmacovigilance is a network of public institutions and contract research organizations coordinated by the European Medicines Agency to facilitate the conduct of PASSs and provide guidance on study design, data sources, and analysis .…”

Section: Discussionmentioning

confidence: 99%

Challenges of post‐authorization safety studies: Lessons learned and results of a French study of fentanyl buccal tablet

Gavrielov-Yusim

Bidollari

Kaplan

et al. 2017

Pharmacoepidemiology and Drug

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Despite efforts to increase participation, enrollment in this study was low. Recruitment and retention methods are limited in their capacity to optimally execute a primary data collection in a PASS. For a PASS to provide reliable and valid information on medication use, involvement from health care agencies, regulators, and pharmaceutical companies is needed to establish their importance, drive study participation, and reduce patient withdrawal.

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“…3 This is a great accomplishment for Canada as Western Europe and the United States have noted a decline in the number of medical investigators participating in research over a 10-year period. 4 Canadian contributors in dermatology were not among the highest publishing specialists in The Lancet and the NEJM but did contribute largely to the amount of publishing in dermatology. A previous study published between 1993 and 2007 showed a significant yearly increase in both pediatric and adult dermatology original article publications.…”

mentioning

confidence: 99%