Number of Stromal Precursors in Mouse Bone Marrow and Expression of Cytokine Genes in Primary Cultures of Mouse Bone Marrow Cells during Various Periods after Immunization with S. typhimurium Antigens
Abstract:Administration of S. typhimurium microbial mass to mice was followed by a significant increase (by 3-4 times) in the efficiency of cloning and number of stromal precursors in the femoral bone marrow. These parameters were maximum on days 1-3, but returned to normal by the 8th-15th day after immunization. As differentiated from intact animals, the expression of genes for proinflammatory cytokines IL-1β (day 1 after immunization), IL-6 (days 1-3), TNF-α (days 1, 3, and 6), and IFN-α (days 1-3) was detected in bo… Show more
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