Number of lymph node metastases and its prognostic significance in early gastric cancer: A multicenter italian study

Abstract

Nodal involvement confirmed to be a significant prognostic factor. In view of the trend to a lower risk of recurrence when more than 15 nodes were retrieved and the better staging achieved we consider D2 lymphadenectomy the treatment of choice.

Incidence of lymph node metastasis and the feasibility of endoscopic resection for undifferentiated-type early gastric cancer

“…Radical surgery with lymph node dissection has provided an excellent therapeutic outcome; the 5-year survival rate after curative resection is more than 90%, including fi ndings in recent European series [4,14,[16][17][18][19][20][21]. In Japan, analyses of databases containing a large number of pathology reports, patients' histories, and long-term survival data from major leading hospitals have demonstrated that the 5-year cancer-specifi c survival rates of EGC limited to the mucosa or the submucosa are 99% and 95%, respectively [4].…”

Validity of modified gastrectomy combined with sentinel node navigation surgery for early gastric cancer

“…In western countries, Roviello et al [12], in their multicenter retrospective study, confi rmed nodal involvement to be a signifi cant prognostic factor for early gastric cancer. In view of the trend to a lower risk of recurrence when more than 15 nodes were retrieved and the better staging achieved, they concluded that D2 lymphadenectomy was the treatment of choice.…”

Evaluation of Slug Expression is useful for Predicting Lymph Node Metastasis and Survival in Patients with Gastric Cancer

“…EGC is defined as gastric cancer that invades no more deeply than the submucosa, irrespective of lymph node metastasis [33]. It has been reported that about 10-15% of patients with EGC have lymph node metastasis [1,34,35]. Precise prediction of lymph node metastasis status in EGC is a very important issue because ESD has become increasingly popular as a minimally invasive treatment for EGC [36].…”