Number of Lapses during the Psychomotor Vigilance Task as an Objective Measure of Fatigue

Lee, In-Soo; Bardwell, Wayne A.; Ancoli‐Israel, Sonia; Dimsdale, Joel E.

doi:10.5664/jcsm.27766

Cited by 71 publications

(41 citation statements)

References 36 publications

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“…Patients in our study especially showed marked vigilance impairments when they had increased daytime sleepiness. This finding is in keeping with previous studies on impaired sustained attention in sleepy subjects [40][41][42] or in OSA patients [21,22,43]. We found considerable consistency between the objective (vigilance performance test) and the subjective (ESS) measure of sleepiness.…”

Section: Impaired Vigilance In Relation To Both Subjective Sleepinesssupporting

confidence: 92%

Impaired Vigilance Is Associated with Erectile Dysfunction in Patients with Sleep Apnea

Popp

Kleemann

Burger

et al. 2015

The Journal of Sexual Medicine

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Introduction Erectile dysfunction (ED) is frequent in patients with obstructive sleep apnea (OSA) and may act as a surrogate of endothelial dysfunction. Furthermore, impairments of vigilance and sustained attention are also commonly associated with OSA. Aim The purpose of this study was to evaluate whether there is an association between ED and sustained attention deficits. Methods A prospective cross-sectional cohort of 401 male in-patients undergoing diagnostic polysomnography for suspected OSA and a 25-minute sustained attention test was analyzed. ED was assessed using the 15-item International Index of Erectile Function (IIEF-15) questionnaire. The Epworth Sleepiness Scale (ESS) served as a measure of daytime sleepiness. Main Outcome Measure Severity of impaired erectile function (EF) assessed by the IIEF-15, core task parameters of the sustained attention test (i.e., CR: correct reactions; V-CR: variation of correct reactions, CE: commission errors, RT: reaction time; V-RT: variation of reaction times). Results Three hundred eighty-one consecutive patients presenting for in-lab polysomnography were included in the analysis. Impaired EF was diagnosed in 246 patients (65%). With increasing impairment of EF, patients scored significantly worse in all vigilance test parameters and demonstrated more severely diminished vigilance (normal EF: 11.9%, moderately impaired EF: 24.1%, and severely impaired EF: 34.9%). Multivariate regression analyses including established risk factors for ED, OSA, or sleepiness revealed a significant independent association between lower scores for EF and impairments on the following vigilance test variables: odds ratio (95% confidence interval) for V-CR: 0.52 (0.34–0.81), CE: 0.87 (0.80–0.95), and V-RT: 0.91 (0.87–0.96). The ESS was independently associated with both measures of performance instability: odds ratio for V-CR: 6.94 (2.97–16.23) and V-RT: 1.28 (1.14–1.44). Conclusions In OSA patients, the severity of impaired EF was associated with impaired vigilance performance, independent of other known risk factors for ED or OSA and not mediated by sleepiness. Potentially, the findings suggest a direct relationship between vascular or endothelial dysfunction and impairments in both EF and neurobehavioral cognitive function.

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Section: Impaired Vigilance In Relation To Both Subjective Sleepinesssupporting

confidence: 92%

Impaired Vigilance Is Associated with Erectile Dysfunction in Patients with Sleep Apnea

Popp

Kleemann

Burger

et al. 2015

The Journal of Sexual Medicine

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“…Fatigue is a common experience in daily life that can manifest as a feeling of tiredness, reduced energy level, muscle weakness, and cognitive impairments. 1,2 Accord-ing to previous studies among the general population in countries outside Japan, 15-32% of complaints were found to concern fatigue, 3-6 with more women than men tending to complain of fatigue. 4,5 In 1991 in Japan, the Ministry of Health and Welfare (now the Ministry of Health, Labour and Welfare) began a group study on chronic fatigue to elucidate its etiology and clinical conditions.…”

Section: Introductionmentioning

confidence: 77%

Prevalence of fatigue symptoms and correlations in the general adult population

Aritake

Kaneita

Ohtsu

et al. 2014

Sleep and Biological Rhythms

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This study sought to clarify the prevalence and associated factors of subjective fatigue symptoms, by analyzing epidemiological data for a sample of the Japanese population. Data from 1224 individuals (539 men and 685 women) aged ≥20 years were subsequently analyzed. Prevalence of fatigability was 17.2% (n = 211) and that of residual fatigue was 13.6% (n = 167), with women showing significantly higher prevalence of both symptoms than men (fatigability: men 12.6% vs women 20.9%, χ 2 = 14.43, P = 0.001; residual fatigue: men 10.0% vs women 16.5%, P = 0.001). Multivariate logistic regression analyses revealed that being female, nonrestorative sleep, decreased quality of life, and stress showed significant positive associations with fatigability and residual fatigue. However, a significant positive association was found between depressed mood and fatigability, and short sleep duration and long working hours (≥9 h) were specifically significantly positively associated with residual fatigue. Sleep hygiene instruction and a psychiatric approach are needed to reduce fatigue in the Japanese population.

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“…Fatigue-related impairments. The Psychomotor Vigilance Task is a reaction time task which is widely used to discriminate between sleep deprived subjects and alert subjects (Lee et al, 2010;Basner et al, 2011). Lapses in attention as measured by the PVT indicate fatiguerelated impairments that are caused by either sleep loss or time-on-task (Warm et al, 2008).…”

Section: Methodsmentioning

confidence: 99%

Informal fatigue-related risk management in the emergency department: A trade-off between doing well and feeling well

et al. 2020

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Number of Lapses during the Psychomotor Vigilance Task as an Objective Measure of Fatigue

Cited by 71 publications

References 36 publications

Impaired Vigilance Is Associated with Erectile Dysfunction in Patients with Sleep Apnea

Impaired Vigilance Is Associated with Erectile Dysfunction in Patients with Sleep Apnea

Prevalence of fatigue symptoms and correlations in the general adult population

Informal fatigue-related risk management in the emergency department: A trade-off between doing well and feeling well

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