Number of acquired melanocytic nevi in patients with melanoma and control subjects in Japan: nevus count is a significant risk factor for nonacral melanoma but not for acral melanoma

The prevalence of melanocytic nevi on the soles in the Japanese population

“…Rokuhara et al also showed that the number of acquired nevi on the soles, palms, and nail apparatus was not different between patients with acral melanoma and a control group. 13 We surveyed only plantar nevi in our study; our results are similar to those of the aforementioned report.…”

“…15,16 In addition, it has been shown that the number of acquired nevi on the body, except for the scalp and genital areas, increases with age, and the average number reached a peak in the 20-to 39-year-old age group. 13 The number of common acquired melanocytic nevi increases with a child's age and is dependent on various internal and external factors (ie, genetics; hormonal, constitutional, and pigmentary characteristics; sun exposure; and geographic latitude). 17 Our data were similar to those obtained from studies of nevi on the entire body.…”

“…7 However, it was suggested that acquired nevi on the soles is not a risk factor for acral melanoma in the Japanese population. 13 As yet, there has not been a detailed investigation on the epidemiology of melanocytic nevi on the soles in the Japanese population. In this study, we investigated the prevalence and dermatoscopic characteristics of plantar melanocytic nevi in patients with and without malignant melanoma and compared the two groups.…”

Akral Melanositik Nevüslerin Dermoskopik Özellikleri

“…Ancak palmoplantar bölge ve tırnaktaki nevüs sayısı ile akral melanom riski arasında bir iliş-ki olmadığını göstermişlerdir. 9 Bizim çalışmamızda da melanom teşhis edilen hastada bir adet nevüs bulunurken, fazla nevüsü olan hastaların lezyonları benin özellikte idi. Lezyonların lokalizasyonlarına göre dağılımlarına bakıldığında en sık iç arkus (%20) ve parmaklarda (%18,4) yerleştikleri görülmüştür.…”

Introduction to Skin Cancer

“…Having a large number of acquired nevi-often considered to be more than 50-puts a person at increased risk for melanoma [46]. This finding has been demonstrated not only in white populations but also recently in Japanese populations [47]. A dysplastic or atypical nevus is an important marker for melanoma [48].…”