Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. 1. Synthesis and interconversion of simple esters of ribomononucleotides

Reminiscences of Leon A. Heppel

“…Also, the early steps in the hydrolysis of RNA by pancreatic ribonuclease were worked out in a collaboration with Paul R. Whitfeld (6). This work lead to the isolation, by paper chromatography and paper electrophoresis, of cyclic terminal oligonucleotides.…”