Nucleophilic Fluorination of Electron-Deficient Arenes

Abstract

C/ 13 C kinetic isotope effect studies and computational analysis showed that the formation of C-F bond and the cleavage of C-Br bond may occur simultaneously and that there is no evidence of the formation of Meisenheimer complex as the stable intermediate. In the case of 1-chloro-2,4-dinitrobenzene, the corresponding Meisenheimer complex structure is