Nucleophilic Addition to CO Double Bonds

Abstract

H CN HO 97 %, 97 % ee (ref. 23) 83 %, >98 % ee (ref. 26) H CN HO 61 %, 91 % ee (ref. 23) H CN HO 76 %, 93 % ee (ref. 23) H 3 CO H CN HO 78 %, 96 % ee (ref. 23) H 3 C H CN HO H 3 C 95 %, 91 % ee (ref. 22) H CN HO H 3 CO 83 %, 97 % ee (ref. 23) H CN HO PhO 97 %, 92 % ee (ref. 23) 84 %, 95 % ee (ref. 26) H CN HO 85 %, 83 % ee (ref. 22) H 3 CO H CN HO 45 %, 84 % ee (ref. 23) OCH 3 H CN HO 90 %, 80 % ee (ref. 22) F 3 C H CN HO 50 %, 89 % ee (ref. 22) N H H 3 C O O H O 76 %, 93 % ee (ref. 22) Scheme 6.2 132 6 Nucleophilic Addition to CbO Double Bonds 1: 83 %, 97 % ee (R ) (ref. 23) 2: 89 %, 56 % ee (S ) (ref. 33) t-Bu H O 91 %, 66 % ee (ref. 33) i-Pr H O 83 %, 64 % ee (ref. 33) H O 98 %, 74 % ee (ref. 33) n-C 5 H 11 H O 93 %, 81 % ee (ref. 33)