Nucleic Acid Delivery Nanotechnologies for In Vivo Cell Programming
Hannia V. Balcorta,
Veronica G. Contreras Guerrero,
Deepali Bisht
et al.
Abstract:In medicine, it is desirable for clinicians to be able to restore function and imbue novel function into selected cells for therapy and disease prevention. Cells damaged by disease, injury, or aging could be programmed to restore normal or lost functions, such as retinal cells in inherited blindness and neuronal cells in Alzheimer's disease. Cells could also be genetically programmed with novel functions such as immune cells expressing synthetic chimeric antigen receptors for immunotherapy. Furthermore, knockd… Show more
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