Nucleic acid biosensor for DNA hybridization detection using rutin–Cu as an electrochemical indicator

Niu, Shuyan; Wu, Mingliang; Hu, Leng-Zhi; Mei, Zhenhua; Liu, Shufeng

doi:10.1016/j.electacta.2008.09.038

Cited by 21 publications

(10 citation statements)

References 34 publications

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“…The interactions between transition metal complexes and DNA have been a widely investigated subject due to their potential application in the molecular recognition of nucleic acids [12,13]. It has been found that the coordination geometry and ligand donor atom play key roles in determining the binding mode between metal complexes and DNA [14,15]. The metal ion and its flexible valence, which are responsible for the geometry of complexes, also affect the intercalating ability of metal complexes to DNA [16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Locked nucleic acids biosensor for detection of BCR/ABL fusion gene using benzoate binuclear copper (II) complex as hybridization indicator

Lin

Kang

Weng

et al. 2011

Sensors and Actuators B: Chemical

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Section: Introductionmentioning

confidence: 99%

Locked nucleic acids biosensor for detection of BCR/ABL fusion gene using benzoate binuclear copper (II) complex as hybridization indicator

Lin

Kang

Weng

et al. 2011

Sensors and Actuators B: Chemical

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“…Some of the aforementioned activities have also been found in transition-metal complexes of the flavonoids [14], and these complexes are sometimes more effective than the uncomplexed flavonoids [15] [16]. Redox properties of some flavonoids and flavonoid complexes have been investigated by electrochemical [17 -19], pulse radiolysis [20 -22] [24]. Transient spectra in Figs.…”

mentioning

confidence: 99%

On the Ligand‐to‐Metal Charge‐Transfer Photochemistry of the Copper(II) Complexes of Quercetin and Rutin

Torres

Ferraudi

Aguirre

et al. 2011

Helvetica Chimica Acta

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In contrast to the UV-photoinduced ligand photoionization of the flavonoid complexes of Fe III , redox reactions initiated in ligand-to-metal charge-transfer excited states were observed on irradiation of the quercetin (1) and rutin (2) were flash-irradiated at 351 nm. Transient spectra observed in these experiments showed the formation of radical ligands corresponding to the one-electron oxidation of L and the reduction of Cu II to Cu I . The radical ligands remained coordinated to the Cu I centers, and the substitution reactions replacing them by solvent occurred with lifetimes t < 350 ns. These are lifetimes shorter than the known lifetimes (t > 1 ms) of the quercetin and rutin radicals decay.

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“…Flavonoid complex-based biosensors can be useful in several domains, such as transducing DNA hybridization, drug design, and diagnosis [102,103,105].…”

Section: Interactions Of Flavonoids Metal Complexes With Nucleic Acidsmentioning

confidence: 99%

Flavonoid Complexes as Promising Anticancer Metallodrugs

Uivaroşi¹,

Arbănași²

2017

Flavonoids - From Biosynthesis to Human Health

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Flavonoid metal complexes commonly exhibit an improvement of biological activity compared to the parent ligands. This chapter is focused on the antioxidant and anticanccer properties of flavonoid metal complexes, in correlation with their binding ability to vital macromolecules such as nucleic acids and serum proteins. Perspectives for an adequate formulation of these complexes were also discussed.

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Nucleic acid biosensor for DNA hybridization detection using rutin–Cu as an electrochemical indicator

Cited by 21 publications

References 34 publications

Locked nucleic acids biosensor for detection of BCR/ABL fusion gene using benzoate binuclear copper (II) complex as hybridization indicator

Locked nucleic acids biosensor for detection of BCR/ABL fusion gene using benzoate binuclear copper (II) complex as hybridization indicator

On the Ligand‐to‐Metal Charge‐Transfer Photochemistry of the Copper(II) Complexes of Quercetin and Rutin

Flavonoid Complexes as Promising Anticancer Metallodrugs

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