Nuclear War Survival Skills,

Kearny, Cresson H.

doi:10.21236/ada328301

Cited by 13 publications

(4 citation statements)

References 4 publications

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“…One limitation of this study is the static nature of the derived dosimetry plume presented here, that is, it is based on sampling at a single time point immediately following the nuclear incident. Radiation dispersion and decay are known to have significant effects for hours after an event [33]. Physical dosimeters deposited by radio-controlled drones, for example, at locations specified by geostatistics could provide continuous radiation levels for accurate dynamic modelling of plume evolution.…”

Section: Discussionmentioning

confidence: 99%

Meeting radiation dosimetry capacity requirements of population-scale exposures by geostatistical sampling

Rogan

Mucaki

et al. 2020

PLoS ONE

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Background Accurate radiation dose estimates are critical for determining eligibility for therapies by timely triaging of exposed individuals after large-scale radiation events. However, the universal assessment of a large population subjected to a nuclear spill incident or detonation is not feasible. Even with high-throughput dosimetry analysis, test volumes far exceed the capacities of first responders to measure radiation exposures directly, or to acquire and process samples for follow-on biodosimetry testing. Aim To significantly reduce data acquisition and processing requirements for triaging of treatment-eligible exposures in population-scale radiation incidents. Methods Physical radiation plumes modelled nuclear detonation scenarios of simulated exposures at 22 US locations. Models assumed only location of the epicenter and historical, prevailing wind directions/speeds. The spatial boundaries of graduated radiation exposures were determined by targeted, multistep geostatistical analysis of small population samples. Initially, locations proximate to these sites were randomly sampled (generally 0.1% of population). Empirical Bayesian kriging established radiation dose contour levels circumscribing these sites. Densification of each plume identified critical locations for additional sampling. After repeated kriging and densification, overlapping grids between each pair of contours of successive plumes were compared based on their diagonal Bray-Curtis distances and root-mean-square deviations, which provided criteria (<10% difference) to discontinue sampling.

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Section: Discussionmentioning

confidence: 99%

Meeting radiation dosimetry capacity requirements of population-scale exposures by geostatistical sampling

Rogan

Mucaki

et al. 2020

PLoS ONE

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“…As of 1986, the reference Nuclear War Survival Skills (Kearny, 1986) judged that, ''Switzerland has the best civil defense system, one that already includes blast shelters for over 85 percent of all its citizens.'' They have 300,000 communal bunkers, which another source claims is enough for the entire Swiss population of 7.6 million, with a million spaces to spare.…”

Section: Government Bunkers For Private Citizensmentioning

confidence: 99%

How much could refuges help us recover from a global catastrophe?

Beckstead¹

2015

Futures

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“…Hybridomas were obtained by fusing spleen cells from immunized Balb/c mice and X63/Ag8.653 mouse myeloma cells (25) according to standard procedures (26). Monoclonal specificity was determined by ELISA and immunoblotting.…”

Section: Antibodiesmentioning

confidence: 99%

The 26S rRNA binding ribosomal protein equivalent to bacterial protein L11 is encoded by unspliced duplicated genes in Saccharomyces cerevisiae

Pucciarelli

Remacha

Vilella

et al. 1990

Nucleic Acids Research

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Transformant phages expressing L15, a yeast ribosomal protein which binds to 26S rRNA and interacts with the acidic ribosomal proteins, were isolated by screening a yeast cDNA expression library in lambda gt11 with specific monoclonal antibodies. Using yeast DNA HindIII fragments that hybridize with the cDNA insert from the L15-expressing clones, minilibraries were prepared in pUC18, which were afterward screened with the same cDNA probe. In this way, plasmids carrying two different types of genomic DNA inserts were obtained. The inserts were subcloned and sequenced and we found a similar coding sequence in both cases flanked by 5' and 3' regions with very low homology. Sequences homologous to the consensus TUF-binding UAS boxes are present in the 5' flanking regions of both genes. Southern analysis revealed the presence of two copies of the L15 gene in the Saccharomyces cerevisiae genome, which are located in different chromosomes. The encoded amino acid sequence corresponds, as expected, to protein L15 and shows a high similarity to bacterial ribosomal protein L11.

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Nuclear War Survival Skills,

Cited by 13 publications

References 4 publications

Meeting radiation dosimetry capacity requirements of population-scale exposures by geostatistical sampling

Meeting radiation dosimetry capacity requirements of population-scale exposures by geostatistical sampling

How much could refuges help us recover from a global catastrophe?

The 26S rRNA binding ribosomal protein equivalent to bacterial protein L11 is encoded by unspliced duplicated genes in Saccharomyces cerevisiae

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