Nuclear reaction measurements of 95MeV/u 12C interactions on PMMA for hadrontherapy

Braunn, B.; Labalme, M.; Ban, G.; Chevallier, M.; Colin, J.; Cussol, D.; Dauvergne, D.; Fontbonne, J.M.; Haas, Franz; Guertin, Arnaud; Lebhertz, D.; Foulher, F. Le; Pautard, C.; Ray, C.; Rousseau, M.; Salsac, M. D.; Stuttgé, L.; Testa, É.; Testa, M.

doi:10.1016/j.nimb.2011.08.010

Cited by 31 publications

(41 citation statements)

References 16 publications

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“…Similar simulations were made for protons with energy 150 MeV, and 12 C and 16 O ions at 100 and 200 MeV/nucleon which are of the practical medical interest in hadron therapy. Collimator thickness is determined by the range of ions in a specific material.…”

Section: Monte Carlo Simulations For the Fractionated Hadron Radiatiomentioning

confidence: 86%

Shaping and monitoring of the mini-beam structures for the spatially fractionated hadron radiation therapy

Momot¹,

Kovalchuk²,

Okhrimenko

et al. 2016

Nucl. Phys. At. Energy

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Design of collimators and their effectiveness for the purposes of the fractionated mini-beam hadron radiation therapy were evaluated by Monte Carlo simulations. The calculations have been performed for proton, carbon and oxygen ion beams at the energies relevant for medical applications. Micropixel metal and hybrid detectors were tested for measuring charged particles intensity distribution in multi-beam structures shaped by slit or matrix collimators exploring low energy proton beam at the Tandem generator (INR NASU, Kyiv). The results obtained illustrate reliable performance of the designed collimators as well as hybrid and metal microdetectors for measuring and imaging in real time the proton intensity distribution over mini-beam structures.Keywords: spatially fractionated hadron radiation therapy, beam collimators, Monte Carlo simulation of dose distribution, monitoring of spatial distribution of the intensity of the charged particle beams, micropixel metal and hybrid detectors.

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Section: Monte Carlo Simulations For the Fractionated Hadron Radiatiomentioning

confidence: 86%

Shaping and monitoring of the mini-beam structures for the spatially fractionated hadron radiation therapy

Momot¹,

Kovalchuk²,

Okhrimenko

et al. 2016

Nucl. Phys. At. Energy

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“…The most recent measurements of this kind were performed for carbon ion collisions with water [22][23][24][25][26]. These tests showed that fragmentation products are peaked in the forward region and mostly contained within few degrees of the beam axis, apart from protons that represent the largest sample and show tails at large emission angles and energies (see Figure 6).…”

Section: Nuclear Physics: What Really Mattersmentioning

confidence: 99%

“…Recent studies have been focused on the possibility of exploiting secondary particle production (and in particular the high penetrating proton component) for monitoring purposes, since it can be used to estimate the position of the distal edge of the dose profile. Beyond the experimental studies of carbon ion in water [22][23][24][25] mentioned in Section 3, measurements performed at small angle [79,80] suggested that, using solid state tracking devices at 30 • with respect to the beam direction, the distal edge of the beam could be estimated with an accuracy of 1.3 mm. In addition, variations in the beam width could be measured with a precision of 0.9 mm.…”

Section: Detection Of Charged Particlesmentioning

confidence: 99%

Nuclear physics and particle therapy

Battistoni

Mattei

Muraro

2016

Advances in Physics: X

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The use of charged particles and nuclei in cancer therapy is one of the most successful cases of application of nuclear physics to medicine. The physical advantages in terms of precision and selectivity, combined with the biological properties of densely ionizing radiation, make charged particle approach a clinically preferred choice in a number of cases. Hadron therapy is in continuous development and nuclear physicists can give important contributions to this discipline. In this work, some of the relevant aspects in nuclear physics will be reviewed. ARTICLE HISTORY

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“…Experimental studies of carbon ion collisions with water reported in refs. [26][27][28][29] showed that fragmentation products are peaked in the forward region and mostly contained within few degrees of the beam axis, apart from protons, that represent the largest sample and show tails at large emission angles and energies. Other measurements performed at small angle [30,31] suggested that, using solid state tracking devices at 30 o with respect to the beam direction, the distal edge of the beam could be estimated with an accuracy of 1.3 mm.…”

Section: Detection Of Charged Particlesmentioning

confidence: 99%

Nuclear physics and particle therapy

Battistoni

2016

EPJ Web of Conferences

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The use of charged particles and nuclei in cancer therapy is one of the most successful cases of application of nuclear physics to medicine. The physical advantages in terms of precision and selectivity, combined with the biological properties of densely ionizing radiation, make charged particle approach an elective choice in a number of cases. Hadron therapy is in continuous development and nuclear physicists can give important contributions to this discipline. In this work some of the relevant aspects in nuclear physics will be reviewed, summarizing the most important directions of research and development.

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Nuclear reaction measurements of 95MeV/u 12C interactions on PMMA for hadrontherapy

Cited by 31 publications

References 16 publications

Shaping and monitoring of the mini-beam structures for the spatially fractionated hadron radiation therapy

Shaping and monitoring of the mini-beam structures for the spatially fractionated hadron radiation therapy

Nuclear physics and particle therapy

Nuclear physics and particle therapy

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