Nuclear protein in testis (NUT) carcinoma diagnosed using only FNA material in the absence of a histological sample

Abstract

This is a recently described rare, genetically defined aggressive carcinoma arising predominantly in the mid line structures. Here, we refine the cytomorphological features of this rare tumour. Accurate diagnosis is important to inform prognosis and guide management as new and ongoing clinical trials may offer effective treatment in the future.

The Utility of Fine Needle Aspiration (FNA) Biopsy in the Diagnosis of Mediastinal Lesions

“…Pleomorphism and multinucleation can be present along with focal keratinization. Nuclei are minimally irregular, and background necrosis and karryorhetic debris are usually evident [44,45]. Thymic carcinomas on FNAs exhibit features similar to their malignant counterparts derived from other organs and vary cytologically by subtype.…”

“…Pleomorphism and multinucleation can be present along with focal keratinization. Nuclei are minimally irregular, and background necrosis and karryorhetic debris are usually evident [44,45].…”