Abstract. This paper presents results of both microscopical and semi-empirical calculations of single-particle characteristics of nuclei and nuclear binding energies, as well as their root-mean-square radii, excitation energies and transition rates in the long chain of Sn isotopes, from the extremely neutron deficient 100 Sn up to neutron excess 136 Sn, where the experimental information is available by now. The comprehensive comparison with the experimental data is carried out.Nuclear binding energies B, as well as one-nucleon separation energies S , are the major nuclear characteristics that define borders of nuclear stability and the decay modes of nuclei. Study of evolution of nuclear properties in the long chains of isotopes or isotones, from the extremely proton-excess up to the extremely neutron-excess nuclei is of special theoretical interest, as here one can check the adequacy of the used theoretical models in the broad interval of (N − Z)/A. Formerly, [1] we studied in details the chain of the N = 82 isotones. Different long chain is represented by the sequence of the nickel isotopes from 48 Ni up to 78 Ni, where all nuclei, except for 78 Ni, turn out to be discovered by the present time. The mentioned chain is of special interest as it includes doubly-magical nucleus 48 Ni (which is an extremely proton-excess one), and 78 Ni (the last one is strongly neutron-excess, and also the doublymagical nucleus). This chain also includes doubly magical 56 Ni and semi-magical 68 Ni. The mentioned series of isotopes was theoretically analyzed by us in [2]. Another long isotopical chain is offered by the succession of tin isotopes having Z = 50. The experimental data are available from 102 Sn (N = 52) up to 136 Sn (N = 86). These nuclei are theoretically studied by us here.For description of global properties of these isotopes we apply the Hartree-Fock-Bogoliubov method. We also use the approach based on the phenomenological mean field potential that was defined by us before [3]. This potential correctly takes into account isovector terms, which is very important when we consider long isotopical chains of nuclei. Here, we examine global properties of nuclei, such as their masses, root-mean-square radii of nucleon distributions, one-and two-nucleon separation energies, as well as single-particle energies of protons and neutrons. We also study excitation energies of nuclei, as well as the reduced transition rates as respect to the electromagnetic and weak transitions.To define nuclear binding energies B in the self-consistent approach, we performed calculations based on the HF+BCS procedure that employs the Skyrme interaction and constant pairing with the corresponding proton and neutron a e-mail: visakov@thd.pnpi.spb.ru pairing constants G p and G n to account for pairing correlations. In this case, one can represent the total energy of an even-even nuclei in its ground state in the following form, see the details in [4,5]:Here and below, "n" refers to neutrons, while "p" to protons. Pairing correlations in the Ha...