1983
DOI: 10.1002/ana.410130603
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Nuclear magnetic resonance imaging in multiple sclerosis

Abstract: Ten patients with definite multiple sclerosis underwent hydrogen nuclear magnetic resonance imaging with a 3.5 kilogauss superconducting magnet, using the inversion recovery and spin-echo techniques of signal acquisition. Results were compared with high-resolution x-ray computed tomography. Spin-echo images demonstrated abnormal regions as areas of variably increased signal intensity. The contrast between abnormal and normal white matter improved as the intervals between sequential radiofrequency pulses and be… Show more

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Cited by 172 publications
(26 citation statements)
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“…Early reports pointed out a high incidence of Devic's disease, accounting for 64.8% of 270 cases of demyelinating disease in Japan (ll, 14). (20)(21)(22). This difference may reflect the difference of clinical forms; among 16 patients who had normal MRI in the present series, 7 were the optic-spinal form.…”
Section: Methodsmentioning
confidence: 65%
“…Early reports pointed out a high incidence of Devic's disease, accounting for 64.8% of 270 cases of demyelinating disease in Japan (ll, 14). (20)(21)(22). This difference may reflect the difference of clinical forms; among 16 patients who had normal MRI in the present series, 7 were the optic-spinal form.…”
Section: Methodsmentioning
confidence: 65%
“…A ressonância magnética é um método bastante sensível para detecção das lesões da esclerose múl-tipla, especialmente se comparada à tomografia computadorizada 8,10,11 . Anormalidades no exame de tomografia computadorizada são encontradas em apenas 30 a 52% dos pacientes com esclerose múl-tipla [12][13][14] , enquanto a RM detecta alterações em 87 a 100% dos pacientes 8,10 .…”
Section: Discussionunclassified
“…Anormalidades no exame de tomografia computadorizada são encontradas em apenas 30 a 52% dos pacientes com esclerose múl-tipla [12][13][14] , enquanto a RM detecta alterações em 87 a 100% dos pacientes 8,10 . Além disso, a ressonância magnética é mais confiável que a tomografia computadorizada pela melhor visibilização da fossa posterior, local em que são relativamente freqüentes placas de desmielinização 11 e pela possibilidade de se obter cortes coronais e sagitais.…”
Section: Discussionunclassified
“…Однако, по мнению других авторов, гиперинтенсивные сигналы МР в Т2 ВИ, локализованные в ПИКС КСТ, не явля- ются специфичными для больных с БАС, так как в редких случаях аналогичные сигналы выявля-лись и у здоровых добровольцев [30]. Известно, что при МРТ-исследовании многооча-говые изменения в веществе головного мозга могут встречаться при разных заболеваниях, таких как рассеянный склероз, цереброваскулярная болезнь, обструктивная или нормотензивная гидроцефалия, деменция, и у пожилых пациентов без деменции, и при других заболеваниях центральной нервной системы [12,22,24,28]. Однако следует отметить, что у этих больных, так же как у пациентов груп-пы сравнения, не было выявлено симметричных очагов гиперинтенсивного сигнала в Т2 ВИ в суб-кортикальных отделах лобной доли, семиовальном центре, внутренней капсуле и ножках мозга, т. е. в ПИКС КСТ.…”
Section: обс у ж дениеunclassified