Nuclear levels and structure from the decays of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msup><mml:mrow /><mml:mrow><mml:mn>213</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math>Bi and<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msup><mml:mrow /><mml:mrow><mml:mn>209</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math>Tl

Ardisson, G.; Barci, V.; Samad, O. El

doi:10.1103/physrevc.57.612

Cited by 22 publications

(12 citation statements)

References 20 publications

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“…Noteworthy is the fact that the abovementioned transition at 868 keV has not been observed in our data set, it is correlated neither to the X-rays of Po nor to the transitions newly assigned to 213 Po. Thus we do not confirm the previously proposed location of the 13/2 + yrast state at 868 keV [16]. A possible assignment of the 868 keV state observed in the β-decay of 213 Bi will be discussed in the following section.…”

Section: Resultscontrasting

confidence: 99%

“…These excited states are not expected to be populated by a reaction induced by heavy ions, since their spin values are very close to the one of the 213 Po ground state (I π =9/2 + ). The last study of the β-decay of 213 Bi [16] has led to the identification of a new state, at 868.0 keV, which mainly de-excites towards the ground state. Its spin value, I=13/2, was proposed on the basis of the comparison with results of semi-empirical shell-model calculations.…”

Section: Resultsmentioning

confidence: 99%

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High-spin states in the five-valence-particle nucleusPo213

Astier

Porquet²

2011

Phys. Rev. C

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Excited states in 213 Po have been populated using the 18 O + 208 Pb reaction at 85 MeV beam energy and studied with the Euroball IV γ-multidetector array. The level scheme has been built up to ∼2.0 MeV excitation energy and spin I ∼ 25/2 from the triple γ-coincidence data. Spin and parity values of several yrast states have been assigned from the γ-angular properties. The configurations of the yrast states are discussed using results of empirical shell-model calculations and by analogy with the neighbouring nuclei. The spin and parity values of several low-spin states of 213 Po previously identified from the β-decay of 213 Bi are revised.

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Section: Resultscontrasting

confidence: 99%

Section: Resultsmentioning

confidence: 99%

High-spin states in the five-valence-particle nucleusPo213

Astier

Porquet²

2011

Phys. Rev. C

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“…For a-particles, 213 Bi was used with a half-life of 45.6 min and decays by a branched pathway by a-and h-emissions to stable 209 Bi (32). Of the emitted energy, 80% is deposited by a-particles with energies of 8.4 MeV (79%) and 5.9 MeV (1%; ref.…”

Section: Dosimetry Radiation Exposure and Radionuclidesmentioning

confidence: 99%

Breaking Chemoresistance and Radioresistance with [213Bi]anti-CD45 Antibodies in Leukemia Cells

Friesen¹,

Glatting²,

Koop³

et al. 2007

Cancer Research

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Chemoresistance and radioresistance are considered one of the primary reasons for therapeutic failure in leukemias and solid tumors. Targeted radiotherapy using monoclonal antibodies radiolabeled with A-particles is a promising treatment approach for high-risk leukemia. We found that targeted radiotherapy using monoclonal CD45 antibodies radiolabeled with the A-emitter 213 Bi ([ 213 Bi]anti-CD45) induces apoptosis, activates apoptosis pathways, and breaks B-irradiation-, ;-irradiation-, doxorubicin-, and apoptosis-resistance in leukemia cells. In contrast to B-irradiation-, ;-irradiation-, and doxorubicin-mediated apoptosis and DNA damage, [213 Bi] anti-CD45-induced DNA damage was not repaired, and apoptosis was not inhibited by the nonhomologous endjoining DNA repair mechanism. Depending on the activation of caspase-3, caspase-8, and caspase-9, [213 Bi]anti-CD45 activated apoptosis pathways in leukemia cells through the mitochondrial pathway but independent of CD95 receptor/ CD95 ligand interaction. Furthermore, [213 Bi]anti-CD45 reversed deficient activation of caspase-3, caspase-8, and caspase-9, deficient cleavage of poly(ADP-ribose) polymerase, and deficient activation of mitochondria in chemoresistant and in radioresistant and apoptosis-resistant leukemia cells. These findings show that [213 Bi]anti-CD45 is a promising therapeutic agent to break chemoresistance and radioresistance by overcoming DNA repair mechanisms in leukemia cells and provide the foundation for discovery of novel anticancer compounds. [Cancer Res 2007;67(5):1950-8]

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“…However, as already discussed [5], these authors used a 229 Th equilibrium source, partly contaminated by 228 Th, and high energy y-lines from decay products of both 229 Th ( 209 T1,.. ) and 228 Th ( 2,2 Bi, 208 T1.. ) led to a high Compton contribution in the resulting spectrum. Consequently, y-lines in the energy range 300-800 keV, which could be emitted by high-energy 225 Ra levels, observed by direct α-spectroscopy [4], could be masked in the spectrum measured with the 229 Th-228 Th equilibrium mixture.…”

Section: Introductionmentioning

confidence: 95%