NTRK rearranged spindle cell neoplasm of the uterine cervix: a rare case report and literature review
Xiaoxia Jiang,
Shao Zhang,
Lin Wu
et al.
Abstract:Background
Neurotrophic tyrosine receptor kinase (NTRK) rearranged spindle cell neoplasm is an emerging group of molecularly defined rare soft tissue tumors, often presenting with a monotonous spindle cell morphology, infiltrative growth, and co-expression of S-100 and CD34 proteins by immunohistochemistry (IHC). Accurate diagnosis necessitates the combination of morphology, immunohistochemistry, and molecular test results, with next-generation sequencing (NGS) as the gold standard. Here, we present a rare ca… Show more
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