ntrathecal Hyperbaric Bupivacaine with Two Different Doses of Clonidine in Lower Limb Orthopaedic Surgery: A Comparative Study

Abstract

Introduction: Spinal anaesthesia has long been known to be of benefit to patients undergoing major orthopaedic procedure. Numerous studies have investigated the effects of intrathecal clonidine co B). Total duration of analgesia and time to 2-segment regression were significantly longer (BC-150 > BC-75 > B). The response was dose dependant. No patients required supplemental analgesia intra-operatively. Onset of motor block was less in BC-75. Duration was significantly higher with combinations (BC-150 > BC-75 > B). The response was again dose dependant. Post-operative analgesia was also significantly longer (BC-150 > BC-75 > B). Minor haemodynamic changes were seen in all three groups. Few complications were reported with BC-150. Conclusion: Small doses of clonidine (≤150 IntroductionSpinal anaesthesia is a simple technique. It provides a deep and fast surgical block through the injection of small doses of local anesthetic solution into the subarachnoid space. Spinal