NT-proBNP changes, oxidative stress, and energy status of hypertrophic myocardium following ischemia/reperfusion injury

Increased Levels of Modified Advanced Oxidation Protein Products are Associated with Central and Peripheral Blood Pressure in Peritoneal Dialysis Patients

“…35,NO. 4 PDI between oxidative stress and NT-proBNP and in another study in which HD patients' oxidative stress associated with the degree of fluid overload (38,39). On the other hand, when we included in the multivariate regression models, in addition to the many other confounders already included in the model, extracellular water volume and NT-proBNP respectively as confounders, the mAOPP level remained independently associated with the central SBP and DBP.…”

Natriuretic Peptides for Risk Stratification of Patients With Valvular Aortic Stenosis

“…20 Eight of 10 studies found that smaller aortic valve area is associated with higher BNP/NT-proBNP levels. 9,10,13,15,19,[21][22][23] Ben-Dor et al 24 found that greater levels of BNP also correlate significantly with higher surgical risk and atrial fibrillation, lower ejection fraction and higher pulmonary, and LV pressures, but they did not find that BNP correlated with aortic valve area, which is in contrast to several studies that found BNP levels are linked to AS severity.…”

“…9,10,13,15,19,[21][22][23] Ben-Dor et al 24 found that greater levels of BNP also correlate significantly with higher surgical risk and atrial fibrillation, lower ejection fraction and higher pulmonary, and LV pressures, but they did not find that BNP correlated with aortic valve area, which is in contrast to several studies that found BNP levels are linked to AS severity. 17,20,25 One possible explanation for this negative finding was a relatively high prevalence of chronic kidney disease (45%) and LV dysfunction, both of which can confound measurement of BNP. With regard to mean aortic valve gradient, 5 of 7 studies listed in Table 2 showed that higher BNP or NT-proBNP levels are associated with a greater mean aortic valve gradient.…”

“…Others have confirmed this relationship between natriuretic peptide levels and LVMI in patients with chronic severe AS. 5,13,15,16,20,21,23,26,27,29,31,32 Eccentric LVH-which may be indicative of a later stage of LV decompensation or mixed regurgitant/stenotic lesions-is associated with higher BNP levels than concentric LVH. 16 The same correlation between BNP levels and LVMI was found in a study of patients undergoing transapical TAVR.…”

“…Peak levels of NT-proBNP are usually seen 24 hours after surgery 20,27 and decrease thereafter. 24 This late decrease in natriuretic peptide levels correlates with reverse myocardial remodeling, specifically a reduction in LV mass and LV dimensions and improvement in LV systolic function.…”