“…In animals, Noxs are activated upon mechanical injury, producing high levels of ROS, which may aid in sterilization of the wound and serve as a chemotactic signal to recruit neutrophils (9). In plants, Noxs have a variety of functions, including response to wounding, herbivory and programed cell death (PCD), where ROS produced by Noxs forms a gradient of H 2 O 2 , indicating that it functions as propagation signal (2,9). Fungi contain from one to three Nox genes (noxA, noxB, noxC), depending on the species (8), and a NoxR protein that regulates NoxA/NoxB (10).…”