NovoSorb Biodegradable Temporizing Matrix for Reconstruction of Multiplanar Degloving Injury of the Upper Limb

Knightly, Nauar; Blacam, Catherine de

doi:10.1097/gox.0000000000004909

Cited by 3 publications

(6 citation statements)

References 10 publications

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“…For relevant defect sizes, the value of secondary wound healing regarding healing time and scar quality should be carefully scrutinized. In all previously published reconstructive pediatric cases, a STSG similar to our protocol was performed [25,27,28]. Similar to these reports, STSG should be performed after BTM to achieve sufficient and high quality final wound closure.…”

Section: Discussionsupporting

confidence: 53%

“…The majority of cases are published for burns, but BTM is becoming increasingly important in reconstructive surgery in adults [26,33]. In children, the indications for BTM in reconstructive soft tissue surgery need to be reviewed, as only three cases have been published to date [25,27,28].…”

Section: Discussionmentioning

confidence: 99%

“…In children, only few case reports describe the use of BTM in burns [5]. To date, only three pediatric cases have been published with BTM in reconstructive surgery [25,27,28].…”

Section: Introductionmentioning

confidence: 99%

“…To date, clinical data for children is limited: only two single pediatric case reports of decollement reconstructions are published. The first on a 7-year-old child with a lower limb degloving injury who was run over by a truck [27], and the second on a 15-year-old boy with a multiplanar upper limb degloving injury [28]. In particular, there is still insufficient data on the incidence of infection, skin shrinkage and functional outcome after two-stage BTM-STSGtreatment in children.…”

Section: Introductionmentioning

confidence: 99%

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NovoSorb® Biodegradable Temporizing Matrix: a novel approach for treatment of extremity avulsion injuries in children

Najem,

Fattouh,

Wintges

et al. 2024

Eur J Trauma Emerg Surg

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Purpose In pediatric population, large soft tissue defects occur in avulsion injuries. In addition to the challenges of primary surgical therapy, elasticity, appearance and function of the scar in children are of crucial importance, especially in the context of body growth. So far various flaps, plasties, skin grafts and dermal substitutes have become established, although infections and skin shrinkage remain challenging. In 2020, a new skin substitute material—NovoSorb® Biodegradable Temporizing Matrix (BTM)—was introduced in Europe for temporary wound closure and tissue regeneration. The aim of this study was to evaluate the value of BTM in pediatric patients. Methods The study included all children treated with BTM after traumatic soft tissue defects following limb avulsion injuries between June 2021 and June 2023 at a university hospital. Results 7 patients with limb avulsion injuries were treated with BTM, 4 boys, 3 girls. Mean age was 6.5 years (2–11 years) at the time of BTM placement. 4/7 had concomitant fractures. BTM was used successfully in all cases, infection did not occur, skin shrinkage was seen in one case. Split thickness skin graft (STSG) after BTM application was performed in average after 33 days (26 to 39 days). Limitations of this study were highlighted. Conclusion BTM is a promising alternative for reconstruction of complex trauma extremity wounds in children following avulsion injuries, even in cases of concomitant bone injuries. Interpretation may be limited by sample size.

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Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

“…In children, only few case reports describe the use of BTM in burns [5]. To date, only three pediatric cases have been published with BTM in reconstructive surgery [25,27,28].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

NovoSorb® Biodegradable Temporizing Matrix: a novel approach for treatment of extremity avulsion injuries in children

Najem,

Fattouh,

Wintges

et al. 2024

Eur J Trauma Emerg Surg

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show abstract

“…The NovoSorb biodegradable temporizing matrix (BTM, PolyNovo Ltd., Melbourne, Australia) is a novel and bioabsorbable synthetic polyurethane bilayer dermal template [3,4] recently introduced to Taiwan. The BTM consists of a 2 mm thick bioabsorbable polyurethane open cell foam matrix covered by a non-biodegradable sealing membrane.…”

Section: Introductionmentioning

confidence: 99%

Strategic Use of Biodegradable Temporizing Matrix (BTM) in Wound Healing: A Case Series in Asian Patients

Chen,

Lin,

Chang

et al. 2024

JFB

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Skin and soft tissue reconstruction has long been based on the reconstructive ladder. However, a skin substitute has become popular due to its predictable outcomes, without donor-site morbidity. The biodegradable temporizing matrix (BTM; NovoSorb, PolyNovo Ltd., Port Melbourne, Australia) is a synthetic skin substitute that has recently gained its clinical application. Compared with those of other dermal templates, the clinical efficacy and performance of the BTM are not well established, especially among the Asian population. This study aims to share our experience and strategy of using BTM in various wound conditions. The data of patients who underwent skin and soft tissue reconstruction with BTM at a single institution between January 2022 and December 2023 were reviewed. The patient demographics, wound characteristics, surgical details, secondary procedures, and complications were recorded and analyzed. Postoperative 6-month photographs were collected and independently evaluated by two plastic surgeons and two wound care center nurses using the Manchester Scar Scale (MSS). This study included 37 patients, consisting of 22 males and 15 females with a mean age of 51.8 years (range, 18–86 years old). The wound etiologies included trauma (67.6%), necrotizing soft tissue infection (16.2%), burns (10.8%), toe gangrene (2.7%), and scar excision (2.7%). The average wound area covered by BTM was 50.6 ± 47.6 cm2. Among the patients, eight received concomitant flap surgery and BTM implantation, 20 (54.1%) underwent subsequent split-thickness skin grafts (STSG), and 17 had small wounds (mean: 21.6 cm2) healed by secondary intention. Infection was the most common complication, affecting six patients (n = 6 [16.2%]), five of whom were treated conservatively, and only one required debridement. Thirty-three patients (89.2%) had good BTM take, and only four had BTM failure, requiring further reconstruction. At the last follow-up, 35 out of the 37 patients (94.6%) achieved successful wound closure, and the total MSS score was 10.44 ± 2.94, indicating a satisfactory scar condition. The patients who underwent BTM grafting without STSG had better scar scores than those who received STSG (8.71 ± 2.60 vs. 11.18 ± 2.84, p = 0.039). In conclusion, the BTM is effective and feasible in treating various wounds, with relatively low complication rates, and it can thus be considered as an alternative for skin and soft tissue reconstruction. When combined with adipofasical flap reconstruction, it achieves a more comprehensive anatomical restoration.

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Application of Novosorb biodegradable temporising matrix in wounds of different aetiologies: a case series

Meagher,

Holmes,

Hanson

et al. 2024

J Wound Care

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This case study series outlines the use of Novosorb biodegradable temporising matrix (BTM, PolyNovo, Australia) in the management of 22 patients, each with a complex wound who attended the vascular department in the University Hospital Limerick between 2021 and 2023. The majority of patients presented with acute conditions (e.g. necrotising fasciitis, crush injuries, compartment syndrome) that initially required high dependency level care. The majority of wounds (21/22, 95%) affected the leg or foot, and one wound was on the chest wall. Each patient had a significant complex wound and, in many cases, was complicated further by the patients' medical condition and comorbidities, which had the potential to cause problematic and delayed healing. The BTM was applied following debridement, as required, and provided a stable base for secondary wound healing or skin grafting, as needed. Of the patients: 12 (54%) healed completely; one (4%) progressed towards complete vascularisation with the BTM in situ; two (9%) underwent major amputations despite successful application of the BTM to lower limb wounds; and one (4%) returned to theatre to have retained clips removed. The remaining six (27%) patients failed to heal completely following BTM application. Ischaemia, infection, vasculitis and underlying osteomyelitis were limiting factors in achieving limb salvage or healing. Declaration of interest: The authors have no conflicts of interest to declare.

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NovoSorb Biodegradable Temporizing Matrix for Reconstruction of Multiplanar Degloving Injury of the Upper Limb

Cited by 3 publications

References 10 publications

NovoSorb® Biodegradable Temporizing Matrix: a novel approach for treatment of extremity avulsion injuries in children

NovoSorb® Biodegradable Temporizing Matrix: a novel approach for treatment of extremity avulsion injuries in children

Strategic Use of Biodegradable Temporizing Matrix (BTM) in Wound Healing: A Case Series in Asian Patients

Application of Novosorb biodegradable temporising matrix in wounds of different aetiologies: a case series

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