Novel wave intensity analysis of arterial pulse wave propagation accounting for peripheral reflections

Alastruey, Jordi; Hunt, Anthony A. E.; Weinberg, Peter D.

doi:10.1002/cnm.2602

Cited by 43 publications

(46 citation statements)

References 64 publications

(115 reference statements)

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“…The inlet of the aorta is connected to a two chamber zero‐dimensional heart model, while the outlet of peripheral vessels connects to a three‐element Windkessel model, which accounts for the microcirculation. A large number of alternative one‐dimensional models can be found in previous studies …”

Section: Mechanical Modelling Of Head Oscillationsmentioning

confidence: 99%

See 1 more Smart Citation

A semi‐active human digital twin model for detecting severity of carotid stenoses from head vibration—A coupled computational mechanics and computer vision method

Chakshu

Carson

Sazonov

et al. 2019

Numer Methods Biomed Eng

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In this work, we propose a methodology to detect the severity of carotid stenosis from a video of a human face with the help of a coupled blood flow and head vibration model. This semi‐active digital twin model is an attempt to link noninvasive video of a patient face to the percentage of carotid occlusion. The pulsatile nature of blood flow through the carotid arteries induces a subtle head vibration. This vibration is a potential indicator of carotid stenosis severity, and it is exploited in the present study. A head vibration model has been proposed in the present work that is linked to the forces generated by blood flow with or without occlusion. The model is used to generate a large number of virtual head vibration data for different degrees of occlusion. In order to determine the in vivo head vibration, a computer vision algorithm is adopted to use human face videos. The in vivo vibrations are compared against the virtual vibration data generated from the coupled computational blood flow/vibration model. A comparison of the in vivo vibration is made against the virtual data to find the best fit between in vivo and virtual data. The preliminary results on healthy subjects and a patient clearly indicate that the model is accurate and it possesses the potential for detecting approximate severity of carotid artery stenoses.

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Section: Mechanical Modelling Of Head Oscillationsmentioning

confidence: 99%

“…A large number of alternative one-dimensional models can be found in previous studies. [19][20][21][22][23][24][25][26][27][28][29][30][31]…”

Section: One-dimensional Haemodynamic Modelmentioning

confidence: 99%

A semi‐active human digital twin model for detecting severity of carotid stenoses from head vibration—A coupled computational mechanics and computer vision method

Chakshu

Carson

Sazonov

et al. 2019

Numer Methods Biomed Eng

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“…The arterial system is represented by a network of elastic tubes, with the LV as the inlet of the circuit and peripheral circulation as terminals. Some relevant contributions on 1D blood flow modelling can be found in recent studies …”

Section: Modelling the Effects Of Ageing On The Human Bodymentioning

confidence: 99%

Influence of ageing on human body blood flow and heat transfer: A detailed computational modelling study

Coccarelli

Hasan

Carson

et al. 2018

Numer Methods Biomed Eng

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Ageing plays a fundamental role in arterial blood transport and heat transfer within a human body. The aim of this work is to provide a comprehensive methodology, based on biomechanical considerations, for modelling arterial flow and energy exchange mechanisms in the body accounting for age‐induced changes. The study outlines a framework for age‐related modifications within several interlinked subsystems, which include arterial stiffening, heart contractility variations, tissue volume and property changes, and thermoregulatory system deterioration. Some of the proposed age‐dependent governing equations are directly extrapolated from experimental data sets. The computational framework is demonstrated through numerical experiments, which show the impact of such age‐related changes on arterial blood pressure, local temperature distribution, and global body thermal response. The proposed numerical experiments show that the age‐related changes in arterial convection do not significantly affect the tissue temperature distribution. Results also highlight age‐related effects on the sweating mechanism, which lead to a significant reduction in heat dissipation and a subsequent rise in skin and core temperatures.

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“…Although a large number of works on blood circulation have been published in the last 30 years [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18], the focus of these works has been limited to isothermal flow. However, understanding energy transport in circulatory systems is vital for applications such as hypothermia and hyperthermia [19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

A Robust Finite Element Modeling Approach to Conjugate Heat Transfer in Flexible Elastic Tubes and Tube Networks

Coccarelli

Nithiarasu

2014

Numerical Heat Transfer, Part A: Applications

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In this work, heat transfer between fluid flow in elastic tubes and external environment is modeled using a robust finite element approach. The transport of energy is coupled to fluid flow that is linked to the pressure and cross-sectional area variations of the tube. The novel model developed is applied to flow and heat transfer in elastic tubes with different geometric and material properties. The effects of reflections due to discontinuities and bifurcations in the tubes are also investigated. To determine the heat transport by conduction in the elastic walls, a radial heat conduction model is also incorporated. The coupled flow equations are solved using the locally conservative Galerkin finite element method, which provides an explicit element-wise conservation of fluxes. Several simulations are performed for different parametric variations to understand the relevant aspects of heat transfer in flexible elastic tubes. The results show that small temperature fluctuations are possible, inline with the pulsatile flow boundary conditions. It is also observed that increased flexibility of tubes leads to better heat transfer between the fluid and the wall. The results clearly indicate that any flow reflections also increase the heat transfer between the fluid and the wall.

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Novel wave intensity analysis of arterial pulse wave propagation accounting for peripheral reflections

Cited by 43 publications

References 64 publications

A semi‐active human digital twin model for detecting severity of carotid stenoses from head vibration—A coupled computational mechanics and computer vision method

A semi‐active human digital twin model for detecting severity of carotid stenoses from head vibration—A coupled computational mechanics and computer vision method

Influence of ageing on human body blood flow and heat transfer: A detailed computational modelling study

A Robust Finite Element Modeling Approach to Conjugate Heat Transfer in Flexible Elastic Tubes and Tube Networks

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