Novel use of porcine urinary bladder matrix for pediatric pilonidal wound care: preliminary experience

Dorman, Robert M.; Bass, Kathryn D.

doi:10.1007/s00383-016-3915-0

Cited by 14 publications

(7 citation statements)

References 19 publications

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“…UBM provides an “off‐the‐shelf” SSP with multiple applications previously reported 4,6,7 . It is easily applied to the wound and, in our study, spared secondary scars from other reconstructive options such as skin grafts and local flaps.…”

Section: Discussionmentioning

confidence: 61%

“…UBM provides an ''off-the-shelf'' SSP with multiple applications previously reported. 4,6,7 It is easily applied to the wound and, in our study, spared secondary scars from other reconstructive options such as skin grafts and local flaps. In addition, it does not require the reconstructive surgeon to have technical skills in microvascular surgery or for patients to endure multiple dressing changes to await healing by secondary intention.…”

Section: Discussionmentioning

confidence: 67%

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Outcomes of Dog Bite Avulsion Injury Reconstruction With Urinary Bladder Matrix

Ong

Nagy

Fincham

et al. 2020

Otolaryngol.--head neck surg.

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Dog bite avulsion injuries of the head and neck are difficult to manage in pediatric patients. This study assesses the outcomes of using porcine urinary bladder extracellular matrix (UBM) for reconstruction of these complete avulsion injuries. Five male pediatric patients underwent reconstruction using UBM. Two (40%) patients underwent reconstruction of the nose; the other 3 patients underwent reconstruction of the forehead, forehead/glabella, and auricle. The average size of the avulsion defect was 7.0 ± 2.4 cm2. No patient developed wound dehiscence, graft loss, or wound infection. Four (80%) patients received pulsed dye laser treatment to improve wound cosmesis. Use of UBM is a safe and effective reconstructive option after dog bite avulsion injuries of the head and neck. Given the advantages of convenient availability and avoidance of donor site morbidity, UBM can be considered for reconstruction of posttraumatic avulsion injuries or Mohs defects.

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Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 67%

Outcomes of Dog Bite Avulsion Injury Reconstruction With Urinary Bladder Matrix

Ong

Nagy

Fincham

et al. 2020

Otolaryngol.--head neck surg.

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“…It has been successfully used to treat wounds with exposed bone and tendon, orbital defects, and radiated wounds (Figure 5). 24 ACell MicroMatrix is contraindicated in wounds with gross contamination or necrotic tissue. It is available in sizes from 20 to 1,000 mg.…”

Section: Acell Micromatrixmentioning

confidence: 99%

Dermal Regenerative Templates in Orthopaedic Surgery

Pidgeon

Hollins

Mithani

et al. 2023

J Am Acad Orthop Surg

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Management of soft-tissue injuries is a critical principle in the treatment of orthopaedic trauma. Understanding the options for soft-tissue reconstruction is vital for successful patient outcomes. Application of dermal regenerative templates (DRTs) in traumatic wounds has created a new rung in the reconstructive ladder bridging the gap between skin graft and flap coverage. There are multiple DRT products with specific clinical indications and mechanisms of action. This review outlines the up-to-date specifications and uses of DRT in commonly seen orthopaedic injuries.

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“…72 ECM powders have been used to bolster ECM sheet monotherapy treatment. The addition of powder treatment has been successful in treating refractory conditions such as pilonidal disease, 73 diabetic foot ulcers, 74 and primary and recurrent anal fistulas. 75 In particular, pilonidal disease is challenging to treat: post-operative sacrococcygeal intergluteal wounds require daily open packing with wound dressings over the course of several months and repeated flap surgeries.…”

Section: Dry Powdermentioning

confidence: 99%

Utility of extracellular matrix powders in tissue engineering

et al. 2018

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Extracellular matrix (ECM) materials have had remarkable success as scaffolds in tissue engineering (TE) and as therapies for tissue injury whereby the ECM microenvironment promotes constructive remodeling and tissue regeneration. ECM powder and solubilized derivatives thereof have novel applications in TE and RM afforded by the capacity of these constructs to be dynamically modulated. The powder form allows for effective incorporation and penetration of reagents; hence, ECM powder is an efficacious platform for 3D cell culture and vehicle for small molecule delivery. ECM powder offers minimally invasive therapy for tissue injury and successfully treatment for wounds refractory to first-line therapies. Comminution of ECM and fabrication of powder-derived constructs, however, may compromise the biological integrity of the ECM. The current lack of optimized fabrication protocols prevents a more extensive and effective clinical application of ECM powders. Further study on methods of ECM powder fabrication and modification is needed.

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Novel use of porcine urinary bladder matrix for pediatric pilonidal wound care: preliminary experience

Cited by 14 publications

References 19 publications

Outcomes of Dog Bite Avulsion Injury Reconstruction With Urinary Bladder Matrix

Outcomes of Dog Bite Avulsion Injury Reconstruction With Urinary Bladder Matrix

Dermal Regenerative Templates in Orthopaedic Surgery

Utility of extracellular matrix powders in tissue engineering

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