Novel use of a 3D printed heart model to guide simultaneous percutaneous repair of severe pulmonary regurgitation and right ventricular outflow tract aneurysm

Jivanji, Salim; Qureshi, Shakeel; Rosenthal, Éric

doi:10.1017/s1047951119000106

Cited by 10 publications

(10 citation statements)

References 5 publications

(4 reference statements)

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“…For complex interventional procedures such as PPVI the benefit of the 3D models has also been reported. Jivanji et al reported a self-expandible valve implantation procedure in the 3D heart model before the implementation procedure ( 22 ).…”

Section: Discussionmentioning

confidence: 99%

Optimizing percutaneous pulmonary valve implantation with patient-specific 3D-printed pulmonary artery models and hemodynamic assessment

Odemis,

AKA,

Ali

et al. 2024

Front. Cardiovasc. Med.

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BackgroundPercutaneous pulmonary valve implantation (PPVI) has emerged as a less invasive alternative for treating severe pulmonary regurgitation after tetralogy of Fallot (TOF) repair in patients with a native right ventricular outflow tract (RVOT). However, the success of PPVI depends on precise patient-specific valve sizing, the avoidance of oversizing complications, and optimal valve performance. In recent years, innovative adaptations of commercially available cardiovascular mock loops have been used to test conduits in the pulmonary position. These models are instrumental in facilitating accurate pulmonic valve sizing, mitigating the risk of oversizing, and providing insight into the valve performance before implantation. This study explored the utilization of custom-modified mock loops to implant patient-specific 3D-printed pulmonary artery geometries, thereby advancing PPVI planning and execution.Material and MethodsPatient-specific 3D-printed pulmonary artery geometries of five patients who underwent PPVI using Pulsta transcatheter heart valve (THV) ® were tested in a modified ViVitro pulse duplicator system®. Various valve sizes were subjected to 10 cycles of testing at different cardiac output levels. The transpulmonary systolic and regurgitation fractions of the valves were also recorded and compared.ResultsA total of 39 experiments were conducted using five different patient geometries and several different valve sizes (26, 28, 30, and 32 mm) at 3, 4, and 5 L/min cardiac output at heart rates of 70 beats per minute (bpm) and 60/40 systolic/diastolic ratios. The pressure gradients and regurgitation fractions of the tested valve sizes in the models were found to be similar to the pressure gradients and regurgitation fractions of valves used in real procedures. However, in two patients, different valve sizes showed better hemodynamic values than the actual implanted valves.DiscussionThe use of 3D printing technology, electromagnetic flow meters, and the custom-modified ViVitro pulse duplicator system® in conjunction with patient-specific pulmonary artery models has enabled a comprehensive assessment of percutaneous pulmonic valve implantation performance. This approach allows for accurate valve sizing, minimization of oversizing risks, and valuable insights into hemodynamic behavior before implantation. The data obtained from this experimental setup will contribute to advancing PPVI procedures and offer potential benefits in improving patient outcomes and safety.

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Section: Discussionmentioning

confidence: 99%

Optimizing percutaneous pulmonary valve implantation with patient-specific 3D-printed pulmonary artery models and hemodynamic assessment

Odemis,

AKA,

Ali

et al. 2024

Front. Cardiovasc. Med.

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“…Jivanji, SGM, et al studied the repair of aneurysm neck occluders and right ventricular outflow tract Venus P valves using a 3D-printed heart model. The encouraging findings of the simulation enabled them to plan complex surgical procedures effectively and achieve successful results [ 12 ]. 3D printing can be used to visually display the geometric relationship between the hypertrophic myocardium, papillary muscle, ventricular muscle band and mitral annulus with different colors and simulate myocardial resection to better grasp the scope of hypertrophic septum resection, define the position and length of the papillary muscle and abnormal ventricular muscle band, and formulate a better surgical plan (Fig.…”

Section: Discussionmentioning

confidence: 99%

Effect of 3D-printed hearts used in left ventricular outflow tract obstruction: a multicenter study

Wang

Liang

et al. 2022

BMC Cardiovasc Disord

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Objective The purpose of this research was to explore the application value of a three-dimensional (3D)-printed heart in surgery for left ventricular outflow tract (LVOT) obstruction. Methods From August 2019 to October 2021, 46 patients with LVOT obstruction underwent surgical treatment at our institution. According to the treatment method, 22 and 24 patients were allocated to the experimental and control groups, respectively. In the experimental group, each patient’s 3D-printed heart model was used for simulated preoperative surgery, and then the Morrow operation was performed. In the control group, only the Morrow operation was performed, without simulated preoperative surgery using a 3D-printed heart model. The intraoperative and postoperative data of patients in the two groups were recorded, and the clinical data of patients were compared between the two groups. Results The operation time, cardiopulmonary bypass time, intraoperative blood loss, hospitalization time, LVOT pressure difference (LVP), postoperative interventricular septal thickness (IST), aortic regurgitation (AR), systolic anterior motion (SAM), and postoperative left ventricular flow velocity (LVFV) were significantly lower in the experimental group than in the control group (P < 0.05). The inner diameter of the left ventricular outflow tract (IDLV) was larger in the experimental group than in the control group (P < 0.05). There was no significant difference in the postoperative ejection fraction, atrioventricular block rate or complication rate between the two groups (P > 0.05). Conclusion A 3D-printed heart model for simulated surgery in vitro is conducive to formulating a more reasonable surgical plan and reducing the trauma and duration of surgery, thereby promoting the recovery and maintenance of the heart.

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“…Jivanji, SGM, et al studied the repair of aneurysm neck occluders and right ventricular out ow tract Venus P valves using a 3D-printed heart model. The encouraging ndings of the simulation enabled them to plan complex surgical procedures effectively and achieve successful results [12] . 3D printing can visually display the geometric relationship between the hypertrophic myocardium, papillary muscle, ventricular muscle band and mitral annulus with different colors and simulate myocardial resection in a 3D model to better grasp the scope of hypertrophic septum resection, de ne the position and length of the papillary muscle and abnormal ventricular muscle band, and formulate a better operation plan (Figure 2).…”

Section: Discussionmentioning

confidence: 99%

Effect of 3D-Printed Hearts Used in Left Ventricular Outflow Tract Obstruction: A Multicenter Study

Wang

Liang

Zhang

et al. 2022

Preprint

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Objective:The purpose of this research was to explore the application value of a three-dimensional (3D)-printed heart in the operation for left ventricular outflow tract (LVOT) obstruction. Methods: From August 2019 to October 2021, 46 patients with LVOT obstruction underwent surgical treatment at Peking University International Hospital, Southwest Medical University Affiliated Hospital of Traditional Chinese Medicine and Guangyuan First People's Hospital. According to the treatment method, 22 cases were allocated to the experimental group and 24 cases to the control group . The operation time, cardiopulmonary bypass time, intraoperative blood loss, hospitalization time, postoperative ejection fraction (EF), left ventricular flow velocity (LVFV), LVOT pressure difference (LVP), postoperative interventricular septal thickness (IST), inner diameter of the left ventricular outflow tract (IDLV), systolic anterior motion (SAM), atrioventricular block rate, aortic regurgitation (AR) rate and surgical complication rate of the two groups were compared. Results: The operation time, cardiopulmonary bypass time, intraoperative blood loss, hospitalization time, LVP, postoperative IST, AR, SAM, and postoperative LVFV of the experimental group were significantly lower than those of the control group (P < 0.05). The IDLV was larger than that of the control group (P < 0.05). There was no significant difference in the postoperative EF, atrioventricular block rate or complication rate between the two groups (P > 0.05). Conclusion: A 3D-printed heart model for in vitro simulation surgery is conducive to formulating a more reasonable surgical plan and reducing surgical trauma and operation time, thereby promoting the recovery and maintenance of the heart.

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Novel use of a 3D printed heart model to guide simultaneous percutaneous repair of severe pulmonary regurgitation and right ventricular outflow tract aneurysm

Cited by 10 publications

References 5 publications

Optimizing percutaneous pulmonary valve implantation with patient-specific 3D-printed pulmonary artery models and hemodynamic assessment

Optimizing percutaneous pulmonary valve implantation with patient-specific 3D-printed pulmonary artery models and hemodynamic assessment

Effect of 3D-printed hearts used in left ventricular outflow tract obstruction: a multicenter study

Effect of 3D-Printed Hearts Used in Left Ventricular Outflow Tract Obstruction: A Multicenter Study

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