Novel ultraviolet‐dermoscopy: Early diagnosis and activity evaluation of vitiligo

Abstract

Background/Objective Polarized dermoscopy, Wood's lamp, and reflectance confocal microscopy were currently commonly used auxiliary technology in vitiligo clinic diagnosis. To improve the efficiency and accuracy of different periods of lesions of vitiligo, we used a novel ultraviolet (UV)‐dermoscopy (Model CH‐UVDS30, Ultraviolet wavelength range of 360<390nm, Chuanghong Science and Technology Company, China) in clinical observation. Materials and Methods Three cases of different periods of vitiligo patients were included in this study. Polarised dermoscopy and novel UV‐dermoscopy (UV wavelength range of 360 nm < λ < 390 nm) were performed at 20 × magnification in polarized and UV modes. Characteristic manifestations of different periods of vitiligo lesions were captured and compared. Results The depigmented and pigmented junctional zone and perifollicular pigmentation areas could be easier and simultaneously identified via UV‐dermoscopy. In a progressive vitiligo patient (woman, 42 years old, face) enhanced perifollicular pigmentation and blurred border were clearly observed. In a stable vitiligo patient (man, 27 years old, right foot) sharply demarcated border and perifollicular depigmentation could be found. In a re‐pigmenting vitiligo patient (woman, 41 years old, neck) telangiectasias and pigmentation reservoirs were observed. Conclusion Novel UV‐dermoscopy, as a miniature and portable device, might help early diagnosis, active/progress judgment, and treatment effect evaluation of vitiligo in the clinic.

In‐depth study of Wood's lamp examination combined with reflective confocal laser scanning microscopy for the guidance of vitiligo staging and treatment

“…In clinical practice, relying only on visual observation of vitiligo lesions to judge the stage of the disease and guide treatment easily results in misjudgment, which also affects the efficacy of treatment. Previous studies have mostly used visual observation and patient recall for the diagnosis of vitiligo, 16,17 which frequently causes misjudgment of lesions with atypical and inconspicuous clinical features. The treatment of vitiligo is based on the presence of Koebner's phenomenon, 18 hypopigmentation, trichromatosis, 19 and confetti‐like depigmentation, as these features have long been thought to be associated with disease activity in vitiligo 20 .…”

Characteristics of vitiligo patients with versus without associated autoimmune thyroid disease

“…The size and type of vitiligo‐affected lesions varied. In this study, vitiligo was diagnosed by two dermatologists based on imaging studies using confocal laser scanning microscopy of the skin, Wood's lamp, and dermoscopy 11 . Medical doctors and dermatologists diagnose AITDs based on clinical manifestations and laboratory tests.…”

“…In this study, vitiligo was diagnosed by two dermatologists based on imaging studies using confocal laser scanning microscopy of the skin, Wood's lamp, and dermoscopy. 11 Medical doctors and dermatologists diagnose AITDs based on clinical manifestations and laboratory tests. Laboratory tests used here included antibodies against thyroid peroxidase and thyroglobulin.…”

Reflectance confocal microscopy clinical applications: Hypopigmented skin lesions in pediatric patients

“…Hypopigmented skin lesions have similar appearances and pose a diagnostic challenge for the clinician, dermoscopy is an useful technique to differential diagnosis, RCM is now believed to be a promising imaging technique for identification of hypopigmented skin diseases. 5,6 We evaluated vitiligo, nevus depigmentosus, lichen striatus, and lichen sclerosus and revealed specific confocal features to support clinical diagnosis and assist with patient management.…”