Novel types of polysaccharidic assemblies

Crescenzi, V.; Imbriaco, David; Velásquez, Cristóbal Lárez; Dentini, Mariella; Ciferri, A.

doi:10.1002/macp.1995.021960912

Cited by 25 publications

(9 citation statements)

References 6 publications

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“…Investigations on novel biocompatible hydrogels based exclusively on polysaccharide chains were reported, where chitosan was linked with dialdehyde obtained from scleroglucan by controlled periodate oxidation . The reaction takes place at pH 1,0 and reduction of the resulting Schiff base is performed with NaCNBH 3 .…”

Section: 3 Hydrogelsmentioning

confidence: 99%

Chitosan Chemistry and Pharmaceutical Perspectives

et al. 2004

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Section: 3 Hydrogelsmentioning

confidence: 99%

Chitosan Chemistry and Pharmaceutical Perspectives

et al. 2004

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“…Lactosilated‐chitosan derivatives (LC 150 , LC 400 , and LC 750 ) were prepared by reductive amination21 of the three different molecular weight chitosan samples. Chitosan (2 g) was dissolved in acqueous solution of 1 vol.‐% acetic acid (200 ml), the pH of which was adjusted to 5.5 by adding NaOH.…”

Section: Experimental Partmentioning

confidence: 99%

Physical Hydrogels of Poly(vinyl alcohol) with Different Syndiotacticity Prepared in the Presence of Lactosilated Chitosan Derivatives

Masci

Husu

Murtas

et al. 2003

Macromolecular Bioscience

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Poly(vinyl alcohol) (PVA) physical hydrogels were prepared by repeated freeze–thawing cycles using aqueous solutions of two PVA samples having different degrees of syndiotacticity, a‐PVA and s‐PVA with 55% and 61% of syndiotactic diads, respectively. The hydrogels were prepared in the presence of different amounts of lactosilated chitosan derivatives (LC) of different molecular weight. The PVA stereoregularity was found to have a dramatic effect on the amount of PVA incorporated into the hydrogels, leading to remarkable differences in the swelling degree and porosity of a‐PVA and s‐PVA hydrogels. A significant amount of LC was retained in the hydrogels after equilibrium swelling. The swelling of the a‐PVA hydrogels was found to increase significantly by increasing the amount of LC while it was only slightly increased in the case of s‐PVA hydrogels. The amount of LC released after equilibrium swelling was lower when chitosan derivatives with higher molecular weights were used. Increased initial concentrations of LC resulted in much higher porosity of the hydrogels. TGA and DSC studies showed that LC is stabilized by the incorporation in the PVA hydrogels. The melting temperature of the crystalline regions of PVA was not significantly influenced by LC. Conversely, the extension of the crystalline domains increased in the presence of LC. The retention of a chitosan derivative bearing β‐D‐galactose side chain residues makes these hydrogels potentially useful as scaffolds for hepatocytes culture.Scanning electron micrographs of PVA‐LC hydrogels: (a) a‐PVA; (b) a‐PVA/LC150 80:20; (c) a‐PVA/LC150 50:50.magnified imageScanning electron micrographs of PVA‐LC hydrogels: (a) a‐PVA; (b) a‐PVA/LC150 80:20; (c) a‐PVA/LC150 50:50.

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“…HA was isolated for the first time from the bovine vitreous body by aqueous acetone extraction and from the human umbilical cord by chloroform extraction. HA can be produced commercially by two methods: chemical extraction of animal tissue and microbial fermentation of [4). However, HA was produced by the previous route, mainly from the cock's combs [5].…”

Section: Introductionmentioning

confidence: 99%

Data Analysis for Hyaluronic Acid Production Using Principal Component Analysis

Riza¹,

Mukhlishien²,

Andriansyah³

2022

Proceedings of the Conference on Broad Exposure to Science and Technology 2021 (BEST 2021)

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Hyaluronic Acid is widely used in proprietary pharmaceutical products such as viscoelastic fluids in ophthalmic surgery, vitreous substitutes, and additional products in Visco for orthopedic disorders: osteoarthritis therapy and sports medicine. To produce HA can be through the growth of microorganisms through experiments. However, experiments have limitations that require a lot of resources. This study tries to find information on experimental data using statistical correlation measurement techniques and principal component analysis. The variables observed from the experimental data were time, pH, and total HA production with changes in the initiation of glucose concentration. The results obtained that the glucose concentration of 20% resulted in the amount of HA with a correlation of 99%.

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Novel types of polysaccharidic assemblies

Cited by 25 publications

References 6 publications

Chitosan Chemistry and Pharmaceutical Perspectives

Chitosan Chemistry and Pharmaceutical Perspectives

Physical Hydrogels of Poly(vinyl alcohol) with Different Syndiotacticity Prepared in the Presence of Lactosilated Chitosan Derivatives

Data Analysis for Hyaluronic Acid Production Using Principal Component Analysis

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