Novel TTG1 Mutants Modify Root-Hair Pattern Formation in Arabidopsis

Long, Yun; Schiefelbein, John

doi:10.3389/fpls.2020.00383

Cited by 26 publications

(46 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, it does not change its expression in response to environmental stimuli [ 139 ]. For these characteristics, ttg1 mutants show pleiotropic effects such as alteration of the development of trichomes; alterations in the accumulation of anthocyanins, causing a transparent head phenotype in the seed coat; and altered development of the root hairs [ 138 , 140 , 141 ]. In general, the whole ternary complex functions as a transcription activator of the anthocyanin biosynthetic genes.…”

Section: Biosynthesis Of Anthocyanins and Gene Expressionmentioning

confidence: 99%

Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases

et al. 2020

View full text Add to dashboard Cite

Anthocyanins are a class of water-soluble flavonoids widely present in fruits and vegetables. Dietary sources of anthocyanins include red and purple berries, grapes, apples, plums, cabbage, or foods containing high levels of natural colorants. Cyanidin, delphinidin, malvidin, peonidin, petunidin, and pelargonidin are the six common anthocyanidins. Following consumption, anthocyanin, absorption occurs along the gastrointestinal tract, the distal lower bowel being the place where most of the absorption and metabolism occurs. In the intestine, anthocyanins first undergo extensive microbial catabolism followed by absorption and human phase II metabolism. This produces hybrid microbial–human metabolites which are absorbed and subsequently increase the bioavailability of anthocyanins. Health benefits of anthocyanins have been widely described, especially in the prevention of diseases associated with oxidative stress, such as cardiovascular and neurodegenerative diseases. Furthermore, recent evidence suggests that health-promoting effects attributed to anthocyanins may also be related to modulation of gut microbiota. In this paper we attempt to provide a comprehensive view of the state-of-the-art literature on anthocyanins, summarizing recent findings on their chemistry, biosynthesis, nutritional value and on their effects on human health.

show abstract

Section: Biosynthesis Of Anthocyanins and Gene Expressionmentioning

confidence: 99%

Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Here, we confirmed by orthologous, phylogenetic and synteny analysis that DcTTG1 cluster with TTG1 ( Table 3 ; Supplementary Table S4 ). TTG1 is constitutively expressed in all major organs, and is a constant member of the MBW complex required for the activation of the anthocyanin pathway and the determination of epidermal cell fate in Arabidopsis [ 99 , 100 , 101 ]. In carrots, DcTTG1 is located in chromosome 6, and its location does not overlap with any anthocyanin-related QTLs previously mapped in carrots ( Table 3 ; Supplementary Table S4 ).…”

Section: Genetics and Genes Controlling Anthocyanin Pigmentation Imentioning

confidence: 99%

Carrot Anthocyanins Genetics and Genomics: Status and Perspectives to Improve Its Application for the Food Colorant Industry

Iorizzo

Curaba

Pottorff

et al. 2020

Genes

View full text Add to dashboard Cite

Purple or black carrots (Daucus carota ssp. sativus var. atrorubens Alef) are characterized by their dark purple- to black-colored roots, owing their appearance to high anthocyanin concentrations. In recent years, there has been increasing interest in the use of black carrot anthocyanins as natural food dyes. Black carrot roots contain large quantities of mono-acylated anthocyanins, which impart a measure of heat-, light- and pH-stability, enhancing the color-stability of food products over their shelf-life. The genetic pathway controlling anthocyanin biosynthesis appears well conserved among land plants; however, different variants of anthocyanin-related genes between cultivars results in tissue-specific accumulations of purple pigments. Thus, broad genetic variations of anthocyanin profile, and tissue-specific distributions in carrot tissues and organs, can be observed, and the ratio of acylated to non-acylated anthocyanins varies significantly in the purple carrot germplasm. Additionally, anthocyanins synthesis can also be influenced by a wide range of external factors, such as abiotic stressors and/or chemical elicitors, directly affecting the anthocyanin yield and stability potential in food and beverage applications. In this study, we critically review and discuss the current knowledge on anthocyanin diversity, genetics and the molecular mechanisms controlling anthocyanin accumulation in carrots. We also provide a view of the current knowledge gaps and advancement needs as regards developing and applying innovative molecular tools to improve the yield, product performance and stability of carrot anthocyanin for use as a natural food colorant.

show abstract

“…28,[34][35][36] TTG2 shows strong specificity for the epidermis, but we also predict expression in some cortex and precursor cells ( Figure 4B). Two key interacting factors of TTG2 that also contribute to epidermis development, GL2 and TTG1, 37,38 showed epidermis expression and had correlated (Pearson correlation with TTG2 across cells for GL2 = 0.91, and TTG1 = 0.47) patterns across all cells (Figure S6B, S6C).…”

Section: Predicting Regulatory Events Using Integrated Scrna and Scatmentioning

confidence: 98%

The regulatory landscape of Arabidopsis thaliana roots at single-cell resolution

Dorrity

Alexandre

Hamm

et al. 2020

Preprint

View full text Add to dashboard Cite

In plants, chromatin accessibility – the primary mark of regulatory DNA – is relatively static across tissues and conditions. This scarcity of accessible sites that are dynamic or tissue-specific may be due in part to tissue heterogeneity in previous bulk studies. To assess the effects of tissue heterogeneity, we apply single-cell ATAC-seq to A. thaliana roots and identify thousands of differentially accessible sites, sufficient to resolve all major cell types of the root. However, even this vast increase relative to bulk studies in the number of dynamic sites does not resolve the poor correlation at individual loci between accessibility and expression. Instead, we find that the entirety of a cell’s regulatory landscape and its transcriptome each capture cell type identity independently. We leverage this shared information on cell identity to integrate accessibility and transcriptome data in order to characterize developmental progression, endoreduplication and cell division in the root. We further use the combined data to characterize cell type-specific motif enrichments of large transcription factor families and to link the expression of individual family members to changing accessibility at specific loci, taking the first steps toward resolving the direct and indirect effects that shape gene expression. Our approach provides an analytical framework to infer the gene regulatory networks that execute plant development.

show abstract

Novel TTG1 Mutants Modify Root-Hair Pattern Formation in Arabidopsis

Cited by 26 publications

References 50 publications

Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases

Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases

Carrot Anthocyanins Genetics and Genomics: Status and Perspectives to Improve Its Application for the Food Colorant Industry

The regulatory landscape of Arabidopsis thaliana roots at single-cell resolution

Contact Info

Product

Resources

About