Novel triphosphorylation polyurethane nanoparticles for blood-contacting biomaterials' coating

Zhang, Jun; Sun, Zhijun; Zhu, Hongmin; Guo, Qiaochu; He, Chengai; Xia, Ao; Hong, Maochun; Huang, Xiaohua; Shen, Jian

doi:10.1039/c5tb01877c

Cited by 4 publications

(1 citation statement)

References 28 publications

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“…It showed that the peaks for phosphorus at 2.0 keV and for silver at 3.0 keV. 44,45 This also indicated that Ag–STPP NPs were sucessfully introduced onto the surface of the PU film.…”

Section: Resultsmentioning

confidence: 92%

Sodium triphosphate–capped silver nanoparticles on a decellularized scaffold-based polyurethane vascular patch for bacterial infection inhibition and rapid endothelialization

Liu

Hong

et al. 2019

Journal of Bioactive and Compatible Polymers

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With increasing incidence rate of cardiovascular diseases and implant-related infections, there is growing demand for vascular patches that can promote endothelialization and resist bacterial infection. In this work, we immobilized sodium triphosphate–capped silver nanoparticles onto a polyurethane film to obtain a composite film and evaluated its in vitro biocompatibility. Subsequently, we anchored sodium triphosphate–capped silver nanoparticles onto a polyurethane-coated decellularized scaffold to prepare a vascular patch and investigated its in vivo performance in a mouse model. The prepared vascular patch demonstrated excellent biocompatibility and potent antibacterial activity against Escherichia coli and Staphylococcus aureus. It still maintained the surgical artery patency at 30 days after implantation. At the same time, the endothelialization at the surgical site was achieved, showing its ability to facilitate endothelialization. Therefore, it may be a promising candidate for combating bacterial infection and treating diseased blood vessels.

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“…It showed that the peaks for phosphorus at 2.0 keV and for silver at 3.0 keV. 44,45 This also indicated that Ag–STPP NPs were sucessfully introduced onto the surface of the PU film.…”

Section: Resultsmentioning

confidence: 92%

Sodium triphosphate–capped silver nanoparticles on a decellularized scaffold-based polyurethane vascular patch for bacterial infection inhibition and rapid endothelialization

Liu

Hong

et al. 2019

Journal of Bioactive and Compatible Polymers

Self Cite

View full text Add to dashboard Cite

show abstract

Surface features and patterning in hydrolytic functionalization of polyurethane films

2021

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Black phosphorus nanosheets-based nanocarriers for enhancing chemotherapy drug sensitiveness via depleting mutant p53 and resistant cancer multimodal therapy

Zhang

Chu

et al. 2019

Chemical Engineering Journal

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Novel triphosphorylation polyurethane nanoparticles for blood-contacting biomaterials' coating

Abstract: Novel polyurethane/sodium triphosphate nanoparticles were synthesized to enhance the blood compatibility of blood-contacting materials.

Cited by 4 publications

References 28 publications

Sodium triphosphate–capped silver nanoparticles on a decellularized scaffold-based polyurethane vascular patch for bacterial infection inhibition and rapid endothelialization

Sodium triphosphate–capped silver nanoparticles on a decellularized scaffold-based polyurethane vascular patch for bacterial infection inhibition and rapid endothelialization

Surface features and patterning in hydrolytic functionalization of polyurethane films

Black phosphorus nanosheets-based nanocarriers for enhancing chemotherapy drug sensitiveness via depleting mutant p53 and resistant cancer multimodal therapy

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