“…A suitable single crystal (CCDC 1887856) of compound 12b for X‐ray diffraction was obtained by recrystallizing with ethyl acetate. Adopting known procedures, the crystal structure resolution was compiled from the collected diffraction data.…”
“…A suitable single crystal (CCDC 1887856) of compound 12b for X‐ray diffraction was obtained by recrystallizing with ethyl acetate. Adopting known procedures, the crystal structure resolution was compiled from the collected diffraction data.…”
“…Docking scores (‐CDOCKER interaction energy) of the best‐fitted poses with the active site at the SDH structure were then recorded. The entire process was done in accordance with our previous work …”
“…In our previous work , we found the perfluoropropanyl group on the quinoline ring can increase the fungicidal activity, so in line with our continued efforts to synthesize novel lead compounds for drug discover , the fungicide tebufloquin was selected as a lead compound, the t ‐Bu group was replaced by perfluoropropanyl group, and the fluorine atom was replaced by hydrogen atom. Then, the ether group was replaced by ester carbonate.…”
A series of new quinoline derivatives containing perfluoropropanyl moiety were designed and synthesized. Their structures were confirmed by 1 H NMR, MS, and elemental analysis. The bioassay results showed that some of them exhibited good control efficacy against Pyricularia oryae. Also, some of the title compounds exhibited good insecticidal activity against Aphis craccivora Koch, Plutella xylostella, Mythimna Separate, and Tetranychus cinnabarinus.
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